Results 61 to 70 of about 4,176,355 (337)

The association between CTSZ methylation in peripheral blood and breast cancer in Chinese women

Frontiers in Oncology, 2023
PurposePrevious studies have shown that DNA methylation in peripheral blood may be associated with breast cancer (BC). To explore the association between the methylation level of the Cathepsin Z (CTSZ) gene in peripheral blood and BC, we conducted a case–
Jinyu Li, Xiajie Zhou, Lixi Li, Longtao Ji, Longtao Ji, Jiaqi Li, Yunhui Qu, Zhi Wang, Zhi Wang, Yutong Zhao, Jie Zhang, Feifei Liang, Feifei Liang, Jingjing Liu, Wanjian Gu, Rongxi Yang, Fei Ma, Liping Dai, Liping Dai   +18 more
doaj   +1 more source

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma [PDF]

, 2015
Accurate assessment of neuroblastoma outcome prediction remains challenging. Therefore, this study aims at establishing novel prognostic tumor DNA methylation biomarkers.
, Berbegall, Ana P., Bienertova-Vasku, Julie, Bown, Nick, Cannoodt, Robrecht, Clément, Nathalie, Combaret, Valérie, De Preter, Katleen, De Wilde, Bram, Decock, Anneleen, Haber, Michelle, Hoyoux, Claire, Laureys, Geneviève, Murray, Jayne, Noguera, Rosa, Ongenaert, Maté, Pierron, Gaelle, Schleiermacher, Gudrun, Schulte, Johannes H., Speleman, Frank, Stallings, Ray L., Tweddle, Deborah A., Van Roy, Nadine, Vandesompele, Jo, Verniers, Kimberly   +24 more
core   +2 more sources

Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib. [PDF]

, 2020
BackgroundTransforming growth factor beta (TGF-β) signalling is involved in the development of hepatocellular carcinoma (HCC). We followed changes in biomarkers during treatment of patients with HCC with the TGF-βRI/ALK5 inhibitor galunisertib ...
Benhadji, Karim A, Cleverly, Ann, Estrem, Shawn T, Faivre, Sandrine, Gane, Ed, Giannelli, Gianluigi, Kelley, Robin K, Lahn, Michael M, Man, Michael, Paradis, Valerie, Raymond, Eric, Santoro, Armando, Smith, Claire, Wang, Shuaicheng   +13 more
core   +2 more sources

Plasma IgG and IgM autoantibodies to COPT1 as potential biomarkers for detection of non-small cell lung cancer

Frontiers in Immunology
BackgroundEarly diagnosis of lung cancer is crucial for improving patient outcomes. Autoantibodies against tumor-associated antigens (TAAs) found in the plasma can serve as biomarkers for lung cancer detection.
Xiaobin Cao, Xiaobin Cao, Jing Li, Siyu Liu, Siyu Liu, Aichen Liu, Lulu Zhang, Fengqi Chen, Yutong Li, Yutong Li, Hanke Ma, Wenke Sun, Songyun Ouyang, Liping Dai, Jingjing Liu   +14 more
doaj   +1 more source

Breast-Lesion Characterization using Textural Features of Quantitative Ultrasound Parametric Maps [PDF]

, 2017
© 2017 The Author(s). This study evaluated, for the first time, the efficacy of quantitative ultrasound (QUS) spectral parametric maps in conjunction with texture-analysis techniques to differentiate non-invasively benign versus malignant breast lesions.
A Ahmed, A Heindl, A König, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, AV Alvarenga, B Sigel, D Sengupta, E Feleppa, EJ Feleppa, EJ Feleppa, EJ Feleppa, EJ Feleppa, EJ Feleppa, F Davnall, FL Lizzi, FL Lizzi, FLL Lizzi, H Tadayyon, H Tadayyon, H Tadayyon, H Tadayyon, J Mamou, JPB O’Connor, K Polyak, KA Wear, KA Wear, KC Balaji, L Sannachi, LX Yao, M Vaidya, MJ Gerdes, ML Oelze, ML Oelze, ML Oelze, ML Oelze, ML Oelze, N Duric, N Sannomiya, R Natrajan, RJ Lavarello, RL Siegel, RM Haralick, S Chicklore, S Tan, T Cover, T Noritomi, TJ Larkin, V Goh, Y Labyed, Y Labyed, Y-Y Liao   +55 more
core   +2 more sources

PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers.

JCI Insight, 2019
BACKGROUND PD-L1 expression and tumor mutational burden (TMB) have emerged as important biomarkers of response to immune checkpoint inhibitor (ICI) therapy.
M. Yarchoan, L. Albacker, Alexander C. Hopkins, M. Montesion, K. Murugesan, Teena Vithayathil, N. Zaidi, N. Azad, D. Laheru, G. Frampton, E. Jaffee   +10 more
semanticscholar   +1 more source

Biomarkers for patients with Wilms tumor: a review

Frontiers in Oncology, 2023
Wilms tumor, originating from aberrant fetal nephrogenesis, is the most common renal malignancy in childhood. The overall survival of children is approximately 90%. Although existing risk-stratification systems are helpful in identifying patients with poor prognosis, the recurrence rate of Wilms tumors remains as high as 15%.
Hongfeng Zheng, Jiangui Liu, Xiuwu Pan, Xingang Cui   +3 more
openaire   +3 more sources

Aberrant Expression and Prognostic Potential of IL-37 in Human Lung Adenocarcinoma

Biomedicines, 2022
Interleukin-37 (IL-37) is a relatively new IL-1 family cytokine that, due to its immunoregulatory properties, has lately gained increasing attention in basic and translational biomedical research.
Panayiota Christodoulou, Theodora-Christina Kyriakou, Panagiotis Boutsikos, Maria Andreou, Yuan Ji, Damo Xu, Panagiotis Papageorgis, Maria-Ioanna Christodoulou   +7 more
doaj   +1 more source

microRNA. Diagnostic Perspective [PDF]

, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +2 more sources

Biomarkers and computational models for predicting efficacy to tumor ICI immunotherapy

Frontiers in Immunology
Numerous studies have shown that immune checkpoint inhibitor (ICI) immunotherapy has great potential as a cancer treatment, leading to significant clinical improvements in numerous cases.
Yurong Qin, Miaozhe Huo, Xingwu Liu, Shuai Cheng Li   +3 more
semanticscholar   +1 more source