Results 71 to 80 of about 2,487,880 (329)

Biomarkers associated with COVID-19 disease progression

Critical reviews in clinical laboratory sciences, 2020
The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is centered on the unpredictable clinical course of the disease that can ...
G. Ponti, M. Maccaferri, C. Ruini, A. Tomasi, T. Ozben   +4 more
semanticscholar   +1 more source

Characteristics and Biomarkers of Ferroptosis

Frontiers in Cell and Developmental Biology, 2021
The induction and consequences of regulated cell death (RCD) are accompanied by changes in gene and protein expression, biochemical pathways, as well as cell morphology and size. Such RCDs have a significant impact on development, tissue homeostasis, and
Xin Chen, P. Comish, D. Tang, R. Kang
semanticscholar   +1 more source

ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]

, 2015
Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md, Bayes, Genis, DI SOMMA, Salvatore, Maisel, Alan S., Md,, Md,, Md,, Mebazaa, Alexandre   +7 more
core   +1 more source

Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis

Respiratory Research, 2021
Background Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of fibrillar collagens in the alveolar space resulting in reduced pulmonary function and a high mortality rate.
H. Jessen, N. Hoyer, T. S. Prior, P. Frederiksen, M. A. Karsdal, D. J. Leeming, E. Bendstrup, J. M. B. Sand, S. B. Shaker   +8 more
doaj   +1 more source

Nonparametric empirical Bayes biomarker imputation and estimation [PDF]

arXiv, 2023
Biomarkers are often measured in bulk to diagnose patients, monitor patient conditions, and research novel drug pathways. The measurement of these biomarkers often suffers from detection limits that result in missing and untrustworthy measurements. Frequently, missing biomarkers are imputed so that down-stream analysis can be conducted with modern ...
arxiv  

Serum micrornas as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma [PDF]

, 2016
The diagnosis of primary sclerosing cholangitis (PSC) is difficult due to the lack of sensitive and specific biomarkers, as is the early diagnosis of cholangiocarcinoma (CC), a complication of PSC.
Alpini, Gianfranco, Alvaro, Domenico, Bernuzzi, Francesca, Bowlus, Christopher L, Carbone, Marco, Eric Gershwin, M, He, Xiao Song, Invernizzi, Pietro, Lleo, Ana, Locati, Massimo, Marabita, Francesco, Marzioni, Marco, Mirolo, Massimiliano, Muri Boberg, Kirsten, Piscaglia, Fabio, Rimassa, Lorenza, Torzilli, Guido, Yang, Guo Xiang   +17 more
core   +2 more sources

Genetics of 35 blood and urine biomarkers in the UK Biobank

Nature Genetics, 2020
Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 individuals).
Nasa Sinnott-Armstrong, Yosuke Tanigawa, D. Amar, N. Mars, Matthew Aguirre, G. Venkataraman, Michael Wainberg, H. Ollila, J. Pirruccello, Junyang Qian, A. Shcherbina, F. Rodriguez, T. Assimes, Vineeta Agarwala, R. Tibshirani, T. Hastie, S. Ripatti, J. Pritchard, M. Daly, M. Rivas   +19 more
semanticscholar   +1 more source

Epilepsy biomarkers [PDF]

Epilepsia, 2013
SummaryA biomarker is defined as an objectively measured characteristic of a normal or pathologic biologic process. Identification and proper validation of biomarkers of epileptogenesis (the development of epilepsy) and ictogenesis (the propensity to generate spontaneous seizures) might predict the development of an epilepsy condition; identify the ...
Engel, Jerome, Pitkänen, Asla, Loeb, Jeffrey A, Dudek, F Edward, Bertram, Edward H, Cole, Andrew J, Moshé, Solomon L, Wiebe, Samuel, Jensen, Frances E, Mody, Istvan, Nehlig, Astrid, Vezzani, Annamaria   +11 more
openaire   +5 more sources

A combined clinical and biomarker approach to predict diuretic response in acute heart failure [PDF]

, 2015
Background: Poor diuretic response in acute heart failure is related to poor clinical outcome. The underlying mechanisms and pathophysiology behind diuretic resistance are incompletely understood.
Bloomfield, Daniel M., Bruno, Noemi, Cleland, John G.F., Cotter, Gad, Damman, Kevin, Davison, Beth, Dittrich, Howard C., Givertz, Michael M., Hillege, Hans L., Metra, Marco, O’Connor, Christopher M., Ponikowski, Piotr, Teerlink, John R., ter Maaten, Jozine M., Valente, Mattia A.E., van Veldhuisen, Dirk J., Voors, Adriaan A.   +16 more
core   +4 more sources

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Journal of Experimental & Clinical Cancer Research, 2019
The extracellular matrix (ECM) plays an important role in cancer progression. It can be divided into the basement membrane (BM) that supports epithelial/endothelial cell behavior and the interstitial matrix (IM) that supports the underlying stromal ...
Neel I. Nissen, Morten Karsdal, Nicholas Willumsen   +2 more
doaj   +1 more source