Results 81 to 90 of about 1,329,782 (302)

Nanomicelles: Types, properties and applications in drug delivery

open access: yesIET Nanobiotechnology, 2021
Nanomicelles are self‐assembling nanosized (usually with particle size within a range of 10 to 100 nm) colloidal dispersions with a hydrophobic core and hydrophilic shell.
Anamika Bose   +3 more
doaj   +1 more source

Materials in particulate form for tissue engineering. 1 Basic concepts [PDF]

open access: yes, 2007
For biomedical applications, materials small in size are growing in importance. In an era where ‘nano’ is the new trend, micro- and nano-materials are in the forefront of developments.
Abazinge   +317 more
core   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Consequences of Sheep Blood Used as Diluting Agent for The Magnetoviscous Effect in Biocompatible Ferrofluids

open access: yesApplied Rheology, 2015
Magnetic nanoparticles suspended in suitable carrier liquids can be adopted for use in biomedicine. For this to be achieved, the biocompatibility of these ferrofluids needs to be ascertained.
Nowak J., Nowak C., Odenbach S.
doaj   +1 more source

Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells

open access: yesIET Nanobiotechnology, 2021
The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Elastohydrodynamic lubrication and wear modelling of the knee joint replacements with surface topography

open access: yesBiosurface and Biotribology, 2018
This numerical study predicted wear of lubricated total knee replacements with the existing of textured surface and the possibility of surface designs to reduce wear.
Leiming Gao   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

In vitro corrosion behaviour of phenolic coated nickel–titanium surfaces

open access: yesBiosurface and Biotribology, 2019
The biocompatibility of implantable nickel–titanium biomaterials relies on the quality of their surfaces. In this study, nickel–titanium surfaces are coated with phenolic thin films of tannic acid and pyrogallol with the purpose of studying their ...
Simon Longela, Athanasios Chatzitakis
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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