Results 41 to 50 of about 123,356 (289)

Biomedical Ontologies: Toward Scientific Debate

open access: yesMethods of Information in Medicine, 2011
SummaryObjectives: Biomedical ontologies have been very successful in structuring knowl edge for many different applications, receiving widespread praise for their utility and potential. Yet, the role of computational ontologies in scientific research, as opposed to knowledge management applications, has not been extensively discussed.
Maojo García, Víctor Manuel   +5 more
openaire   +5 more sources

Biomedical ontologies: a functional perspective [PDF]

open access: yesBriefings in Bioinformatics, 2007
The information explosion in biology makes it difficult for researchers to stay abreast of current biomedical knowledge and to make sense of the massive amounts of online information. Ontologies--specifications of the entities, their attributes and relationships among the entities in a domain of discourse--are increasingly enabling biomedical ...
Daniel L, Rubin   +2 more
openaire   +2 more sources

Matching biomedical ontologies through compact differential evolution algorithm

open access: yesSystems Science & Control Engineering, 2019
Although biomedical ontologies have been widely used in the life science domain, the heterogeneous problem among biomedical ontologies hampers their inter-operability.
Xingsi Xue, Junfeng Chen
doaj   +1 more source

An Effective Method to Measure Disease Similarity Using Gene and Phenotype Associations

open access: yesFrontiers in Genetics, 2019
Motivation: In order to create controlled vocabularies for shared use in different biomedical domains, a large number of biomedical ontologies such as Disease Ontology (DO) and Human Phenotype Ontology (HPO), etc., are created in the bioinformatics ...
Shuhui Su, Lei Zhang, Jian Liu
doaj   +1 more source

Putting Biomedical Ontologies to Work [PDF]

open access: yesEuropean Journal for Biomedical Informatics, 2009
Summary Objectives: Biomedical ontologies exist to serve integration of clinical and experimental data, and it is critical to their success that they be put to widespread use in the annotation of data. How, then, can ontologies achieve the sort of user-friendliness, reliability, cost-effectiveness, and breadth of coverage that is necessary to
B, Smith, M, Brochhausen
openaire   +2 more sources

Context-based refinement of mappings in evolving life science ontologies

open access: yesJournal of Biomedical Semantics, 2023
Background Biomedical computational systems benefit from ontologies and their associated mappings. Indeed, aligned ontologies in life sciences play a central role in several semantic-enabled tasks, especially in data exchange.
Victor Eiti Yamamoto   +2 more
doaj   +1 more source

Ontological modeling of the International Classification of Functioning, Disabilities and Health (ICF): Activities&Participation and Environmental Factors components

open access: yesBMC Medical Informatics and Decision Making, 2021
Background The International Classification of Functioning, Disability and Health (ICF) is a classification of health and health-related states developed by the World Health Organization (WHO) to provide a standard and unified language to be used as a ...
Silvia Cozzi   +2 more
doaj   +1 more source

Cells in experimental life sciences - challenges and solution to the rapid evolution of knowledge

open access: yesBMC Bioinformatics, 2017
Cell cultures used in biomedical experiments come in the form of both sample biopsy primary cells, and maintainable immortalised cell lineages. The rise of bioinformatics and high-throughput technologies has led us to the requirement of ontology ...
Sirarat Sarntivijai   +2 more
doaj   +1 more source

A formal theory for spatial representation and reasoning in biomedical ontologies [PDF]

open access: yes, 2006
Objective: The objective of this paper is to demonstrate how a formal spatial theory can be used as an important tool for disambiguating the spatial information embodied in biomedical ontologies and for enhancing their automatic reasoning capabilities ...
Bittner, Thomas   +2 more
core   +2 more sources

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