Results 61 to 70 of about 18,303,896 (383)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Overview of statistical methods usage in Indian anaesthesia publications

Indian Journal of Anaesthesia, 2022
Background and Aims: Despite the importance of statistics being well established for medical research, it remains a neglected area of understanding and learning.
Asha Tyagi, Devansh Garg, Aparna Mohan, Rashmi Salhotra, Ishita Vashisth, Ananya Agrawal, Sanika Deshpande, Sonali Deep, Sacchidananda Das, Rajeev K Malhotra, Rajeev Pradhan, Aparajita Panda   +11 more
doaj   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

BioFors: A Large Biomedical Image Forensics Dataset [PDF]

arXiv, 2021
Research in media forensics has gained traction to combat the spread of misinformation. However, most of this research has been directed towards content generated on social media. Biomedical image forensics is a related problem, where manipulation or misuse of images reported in biomedical research documents is of serious concern.
arxiv  

RCSB Protein Data Bank: Enabling biomedical research and drug discovery

Protein Science, 2019
Analyses of publicly available structural data reveal interesting insights into the impact of the three‐dimensional (3D) structures of protein targets important for discovery of new drugs (e.g., G‐protein‐coupled receptors, voltage‐gated ion channels ...
D. Goodsell, C. Zardecki, L. D. Di Costanzo, Jose M. Duarte, B. Hudson, Irina Persikova, J. Segura, C. Shao, Maria Voigt, J. Westbrook, Jasmine Y. Young, S. Burley   +11 more
semanticscholar   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Research networking and the role of the medical librarian

Journal of the Medical Library Association
Medical librarians work collaboratively across all units and missions of academic medical centers. One area where librarians can provide key expertise is in the building and maintenance of Research Information Management Systems (RIMS).
Robyn Reed, Matthew J. Eyer, Megan M. Young, Sarah K. Bronson   +3 more
doaj   +1 more source

A Review of Animal Laboratory Practice in the COVID-19 and Safety Concerns

Translational Research in Urology, 2020
The research in biomedical sciences is based on basic research on animals. As a consequence of the coronavirus disease-2019 (COVID-19) pandemic, many research projects involving animal studies have faced interruptions due to the raised concerns about the
Rahil Mashhadi , Fatemeh Khatami, Leyla Zareian Baghdadabad, Alireza Namazi Shabestari, Fateme Guitynavard, Leonardo Oliveira Reis   +5 more
doaj   +1 more source

The impact of sensitizing 1st year undergraduate medical students to research methodology

Journal of Education and Health Promotion, 2022
BACKGROUND: Research is a core essential component of evidence-based medicine. The current study was undertaken to sensitize the undergraduate medical students the concept of biomedical research to sharpen their clinical skills.
Harinder Jot Singh, Sharanjit Kaur, Kuldeep Singh Bhatia   +2 more
doaj   +1 more source

Tracking biomedical articles along the translational continuum: a measure based on biomedical knowledge representation [PDF]

arXiv, 2022
Keeping track of translational research is essential to evaluating the performance of programs on translational medicine. Despite several indicators in previous studies, a consensus measure is still needed to represent the translational features of biomedical research at the article level.
arxiv