Results 71 to 80 of about 18,303,896 (383)
A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications
Genome Medicine, 2017 RNA sequencing (RNA-seq) is a genomic approach for the detection and quantitative analysis of messenger RNA molecules in a biological sample and is useful for studying cellular responses.
A. Haque +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Nanotechnology for Environmental and Biomedical Research [PDF]
Nanomaterials, 2020 Given the high production and broad feasibility of nanomaterials, the application of nanotechnology includes the use of engineered nanomaterials (ENMs) to clean-up polluted media such as soils, water, air, groundwater and wastewaters, and is known as nanoremediation [...]
openaire +3 more sources
Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research.
ALTEX, 2019 This year marks the 60th anniversary of Russell and Burch's pioneering book, The Principles of Humane Experimental Technique. Their 3Rs framework has helped to inspire humane and scientific progress in experimental technique.
Kathrin Herrmann +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Proposing Disciplinary Charter of Research Misconduct: a Qualitative Study [PDF]
Strides in Development of Medical Education, 2010 Background & Objective: The number of research misconduct cases seems to be increasing so the need for developing a disciplinary charter of research misconduct is felt more than ever This study was aimed to propose and develop a charter to determine ...
Nouzar Nakhaee +5 more
doaj
Frontiers in Robotics and AI, 2020 In recent years, artificial intelligence (AI)/machine learning (ML; a subset of AI) have become increasingly important to the biomedical research community. These technologies, coupled to big data and cheminformatics, have tremendous potential to improve
Katharine K. Duncan +3 more
doaj +1 more source
Automatic Glossary of Clinical Terminology: a Large-Scale Dictionary of Biomedical Definitions Generated from Ontological Knowledge [PDF]
arXiv, 2023 Background: More than 400,000 biomedical concepts and some of their relationships are contained in SnomedCT, a comprehensive biomedical ontology. However, their concept names are not always readily interpretable by non-experts, or patients looking at their own electronic health records (EHR). Clear definitions or descriptions in understandable language
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Pre-clinical biomedical research
Revista Cubana de Estomatología, 2015 Introduction: a historical analysis would reveal that the use of animals as test subjects has been both effective and essential. Such a practice has served both to save lives and to answer a variety of biomedical questions.
Denia Morales Navarro
doaj