Results 21 to 30 of about 1,228,491 (361)

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis [PDF]

, 2015
This work was supported by a Merit Scholarship from the Islamic Development Bank (to M.M.U.T.), The Agency for Science, Technology and Research, Singapore (A*STAR) (M.F.M.S), the Medical Research Council (MRC) [NIRG GO800203 and Research Grant MR/L002620/
Edwardson, J Michael, O'Rahilly, Stephen, Rochford, Justin J, Sim, M F Michelle, Talukder, Md. Mesbah Uddin   +4 more
core   +2 more sources

Technology in Rehabilitation: A Conceptual Approach [PDF]

Revista Ciencias de la Salud, 2006
The so called technologies of rehabilitationare part of the strategies that are designed to facilitatethe integration of a person with disabilities;their understanding demands basic conceptualapproaches on technology, engineering andRecibido: 21 de marzo
Margin Martínez Matheus, Adriana Ríos Rincón   +1 more
doaj  

The Panopticon and the performance arena: HCI reaches within [PDF]

, 2009
The impact of new technologies is hard to predict. We suggest the value of theories of performativity in understanding dynamics around the convergence of biomedical and information technology.
Light, Ann, Wright, P.
core   +1 more source

Improvements to the APBS biomolecular solvation software suite [PDF]

, 2017
The Adaptive Poisson-Boltzmann Solver (APBS) software was developed to solve the equations of continuum electrostatics for large biomolecular assemblages that has provided impact in the study of a broad range of chemical, biological, and biomedical ...
Baker, Nathan A., Brandi, Juan, Brookes, David H., Chen, Jiahui, Chun, Minju, Dolinsky, Todd, Engel, Dave, Felberg, Lisa E., Geng, Weihua, Gohara, David W., Head-Gordon, Teresa, Holst, Michael J., Jurrus, Elizabeth, Koes, David R., Konecny, Robert, Krasny, Robert, Li, Peter, Liles, Karina, McCammon, J. Andrew, Monson, Kyle, Nielsen, Jens Erik, Star, Keith, Wei, Guo Wei, Wilson, Leighton   +23 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Fostering digital literacy in the elderly as a means to secure their health needs and human rights in the reality of the twenty-first century

Family Medicine & Primary Care Review, 2018
The rights to life and health are basic human rights but, as life spans increase and societies age, these rights become increasingly difficult to secure. The number of people needing care, nursing, and medical treatment increases – and their expectations
Robert Susło, Mateusz Paplicki, Karol Dopierała, Jarosław Drobnik   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Background-free fibre optic Brillouin probe for remote mapping of micromechanics

, 2020
Brillouin spectroscopy is a century-old technique that has recently received renewed interest, as modern instrumentation has transformed it into a powerful contactless and label-free probe of micromechanical properties for biomedical applications.
Basirun, Carin, Chou, Joshua, Gao, Shoufei, Kabakova, Irina V., Török, Peter, Wang, Yingying, Warkiani, Majid E., Xiang, YuChen   +7 more
core   +1 more source

Grid technology for biomedical applications [PDF]

, 2004
International audienceThe deployment of biomedical applications in a grid environment has started about three years ago in several European projects and national ini-tiatives.
Blanchet, Christophe, BRETON, Vincent, Maigne, L., Montagnat, Johan   +3 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source