Results 41 to 50 of about 1,228,491 (361)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Sociology of low expectations: Recalibration as innovation work in biomedicine [PDF]
, 2015 "This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the ...
Brown Nik +11 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Southwest Research Institute assistance to NASA in biomedical areas of the Technology Utilization program [PDF]
Technology utilization in biomedical areas, particularly for infants and handicapped ...
Culclasure, D. F., Eckhardt, L.
core +4 more sources
Q-enhanced fold-and-bond MEMS inductors [PDF]
, 2008 This work presents a novel coil fabrication technology to enhance quality factor (Q factor) of microfabricated inductors for implanted medical wireless sensing and data/power transfer applications.
Chen, Po-Jui +4 more
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Bulletin of the World Health Organization, 2000 For reasons of equity most OECD countries have chosen to base their funding of health care mainly on public sources. There is an almost universal problem of affordability in the health systems of these countries, arising from the tension between the ...
Jeremy Hurst
doaj
The Use of Health Technology to Enhance the Adherence of Tuberculosis Treatment: A Systematic Review
Jurnal Ners, 2019 Introduction: Disobedience in the context of TB treatment is one of the major problems around the world. Many efforts have been made to improve the adherence to TB treatment; one of them is the utilization of health technology such as digital technology.
Dwi Uswatun Sholikhah +4 more
doaj +1 more source
Non-Contact Video-Based Neonatal Respiratory Monitoring
Children, 2020 Respiratory rate (RR) has been shown to be a reliable predictor of cardio-pulmonary deterioration, but standard RR monitoring methods in the neonatal intensive care units (NICU) with contact leads have been related to iatrogenic complications.
Scott L. Rossol +6 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source