Results 41 to 50 of about 590,133 (265)

Opportunities for Artificial Intelligence in Operational Medicine: Lessons from the United States Military

Bioengineering
Conducted in challenging environments such as disaster or conflict areas, operational medicine presents unique challenges for the delivery of efficient and quality healthcare.
Nikolai Rakhilin, H. Douglas Morris, Dzung L. Pham, Maureen N. Hood, Vincent B. Ho   +4 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study

Health Technology Assessment
Background Glaucoma is a chronic disease of the optic nerve and a leading cause of severe visual loss in the UK. Once patients have been diagnosed, they need regular monitoring at hospital eye services.
Carrie Stewart, Hangjian Wu, Uma Alagappan, Augusto Azuara-Blanco, Anthony J King, Andrew J Tatham, Rodolfo Hernández, Bruce Lowe, Darian Shotton, Nana Appiah, Taylor Coffey, Thenmalar Vadiveloo, Graeme MacLennan, Katie Gillies   +13 more
doaj   +1 more source

PedAMINES: a disruptive mHealth app to tackle paediatric medication errors

Swiss Medical Weekly, 2020
Medication errors are among the most common medical adverse events and an important cause of patient morbidity and mortality, affecting millions of people worldwide each year.
Frédéric Ehrler, Johan N. Siebert
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Nuevas tecnologías en el manejo de la demencia: una revisión de alcance

MedUNAB
RESUMEN Introducción. La demencia es un trastorno con una carga de morbimortalidad global importante. Las nuevas tecnologías son clave para los avances en salud.
Martínez-Torres, Liz Mariana, Mejía-Camacho, Sebastián Camilo, Chavarro-Carvajal, Diego Andrés, Santacruz-Escudero, José Manuel, Cano-Gutiérrez, Carlos Alberto   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The Impact of a Novel Immersive Virtual Reality Technology Associated with Serious Games in Parkinson’s Disease Patients on Upper Limb Rehabilitation: A Mixed Methods Intervention Study

Sensors, 2020
Background: Parkinson’s disease is a neurodegenerative disorder that causes impaired motor functions. Virtual reality technology may be recommended to optimize motor learning in a safe environment.
Patricia Sánchez-Herrera-Baeza, Roberto Cano-de-la-Cuerda, Edwin Daniel Oña-Simbaña, Domingo Palacios-Ceña, Jorge Pérez-Corrales, Juan Nicolas Cuenca-Zaldivar, Javier Gueita-Rodriguez, Carlos Balaguer-Bernaldo de Quirós, Alberto Jardón-Huete, Alicia Cuesta-Gomez   +9 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A Review of Published Articles in the Field of Biomedical Nanotechnology in Medline Database during 2000-2010 [PDF]

Taṣvīr-i salāmat, 2012
Background and objectives : Nanotechnology is a new technology which is increasingly used over the past decade. Due to its great significance, governments are tending to invest greatly on the research and development on nanotechnology in various sectors ...
Peyman Sheikhzade
doaj