Results 51 to 60 of about 1,228,491 (361)

The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]

, 2008
A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R., Jacobs, Russell E., Louie, Angelique Y.   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Opportunities for Artificial Intelligence in Operational Medicine: Lessons from the United States Military

Bioengineering
Conducted in challenging environments such as disaster or conflict areas, operational medicine presents unique challenges for the delivery of efficient and quality healthcare.
Nikolai Rakhilin, H. Douglas Morris, Dzung L. Pham, Maureen N. Hood, Vincent B. Ho   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study

Health Technology Assessment
Background Glaucoma is a chronic disease of the optic nerve and a leading cause of severe visual loss in the UK. Once patients have been diagnosed, they need regular monitoring at hospital eye services.
Carrie Stewart, Hangjian Wu, Uma Alagappan, Augusto Azuara-Blanco, Anthony J King, Andrew J Tatham, Rodolfo Hernández, Bruce Lowe, Darian Shotton, Nana Appiah, Taylor Coffey, Thenmalar Vadiveloo, Graeme MacLennan, Katie Gillies   +13 more
doaj   +1 more source

PedAMINES: a disruptive mHealth app to tackle paediatric medication errors

Swiss Medical Weekly, 2020
Medication errors are among the most common medical adverse events and an important cause of patient morbidity and mortality, affecting millions of people worldwide each year.
Frédéric Ehrler, Johan N. Siebert
doaj   +1 more source

The Value of Value Sets [PDF]

, 2011
A common definition of value set will be provided and fully characterized relative to its proposed uses. We will describe, compare, and contrast several approaches to specifying and referencing value sets in a stable manner over time. The term “value set”
Brinkley, James F, Solbrig, Harold, Tu, Samson, Wynden, Rob   +3 more
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Digital microarrays: single-molecule readout with interferometric detection of plasmonic nanorod labels [PDF]

, 2018
DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species.
Daaboul, George G., Kanik, Fulya Ekiz, Sevenler, Derin, Unlu, M. Selim, Unlu, Nese Lortlar   +4 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source