Results 51 to 60 of about 206,120 (272)
Environment International, 2020 Inhalation from ambient air and cigarette smoke is a common route of human exposure to polycyclic aromatic hydrocarbons (PAHs). Little information is available regarding hepatotoxicities of inhaled PAHs so for.
Fang Li +7 more
doaj +1 more source
Actual metrological conditions for ionizing chamber calibration in radiotherapy [PDF]
Archive of Oncology, 2004 BACKGROUND: Since 1976 it has been recognized that an accuracy of ±5% in the delivery of an absorbed dose to a target volume is necessary for successful therapy treatment.
Spasić-Jokić Vesna M.
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Revista Colombiana de Obstetricia y Ginecología, 2007 Los estudios de evaluación de pruebas diagnósticas son un diseño científico que nos ayuda a determinar la validez y la reproducibilidad de los procedimientos que pueden ser usados en la práctica clínica por médicos y otros profesionales de salud. Este es
María Isabel Castro-Jiménez +2 more
doaj
Science of The Total Environmentعلى الصعيد العالمي، لم يتسبب كوفيد-19 في آثار صحية واجتماعية واقتصادية سلبية هائلة فحسب، بل أدى أيضًا إلى قضايا بيئية مثل الزيادة الهائلة في النفايات الطبية الحيوية. تم توليد النفايات الطبية الحيوية (BMW) من مرافق الرعاية الصحية المركزية (المستشفيات والعيادات ومرافق البحوث) والموسعة (معسكرات الحجر الصحي ومعسكرات اختبار COVID -19 والمنازل المعزولة). يتم
Akshay Srivastava +11 more
openaire +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Health technology assessment of biosimilars worldwide: a scoping review
Health Research Policy and Systems, 2020 Background Health technology assessment (HTA) should provide an assessment of a technology’s effects on health and of the related social, economic, organisational and ethical issues. HTA reports on biosimilars can specifically assess their immunogenicity,
Bruna de Oliveira Ascef +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source