Results 31 to 40 of about 45,122 (251)
Journal of Lipid Research, 1989 We have investigated the transfer of [14C]cholesterol from labeled bovine heart mitochondria and Friend erythroleukemic cells to high density lipoprotein (HDL), low density lipoprotein (LDL), and very low density lipoprotein (VLDL) fractions from human ...
G P van Heusden +2 more
doaj +1 more source
Mechanochemical enzymes and protein machines as hydrodynamic force dipoles: The active dimer model
, 2020 Mechanochemically active enzymes change their shapes within every turnover cycle. Therefore, they induce circulating flows in the solvent around them and behave as oscillating hydrodynamic force dipoles.
Hosaka, Y., Komura, S., Mikhailov, A.
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Charge-induced phase separation in lipid membranes [PDF]
, 2014 The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of ...
Andelman, David +5 more
core +2 more sources
Journal of Lipid Research, 1999 Oxidation of low density lipoproteins (LDL) results in changes to the lipoprotein particle that are potentially pro-atherogenic. To investigate mechanisms contributing to the formation of cholesteryl ester (CE)–core aldehydes (9-oxononanoyl- and 5 ...
Barbara Karten +4 more
doaj +1 more source
TRIM Proteins in Colorectal Cancer: TRIM8 as a Promising Therapeutic Target in Chemo Resistance
Biomedicines, 2021 Colorectal cancer (CRC) represents one of the most widespread forms of cancer in the population and, as all malignant tumors, often develops resistance to chemotherapies with consequent tumor growth and spreading leading to the patient’s premature death.
Flaviana Marzano +4 more
doaj +1 more source
Global minimizers for axisymmetric multiphase membranes [PDF]
, 2012 We consider a Canham-Helfrich-type variational problem defined over closed surfaces enclosing a fixed volume and having fixed surface area. The problem models the shape of multiphase biomembranes.
Choksi, Rustum +2 more
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MembranesThirty-seven steroid drugs of different types were investigated in silico for their environmental and pharmacokinetic properties (partition between soil and water, bioaccumulation in aquatic organisms, ability to be absorbed from the gastrointestinal ...
Anna W. Sobańska +6 more
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Membrane adhesion and domain formation
, 2007 We review theoretical results for the adhesion-induced phase behavior of biomembranes. The focus is on models in which the membranes are represented as discretized elastic sheets with embedded adhesion molecules. We present several mechanism that lead to
Lipowsky, Reinhard, Weikl, Thomas R.
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MoleculesDoxorubicin (DOX) is a commonly used chemotherapeutic drug, from the anthracycline class, which is genotoxic to neoplastic cells via a DNA intercalation mechanism. It is effective and universal; however, it also causes numerous side effects.
Anna Stachowicz-Kuśnierz +3 more
doaj +1 more source
Second order splitting of a class of fourth order PDEs with point constraints [PDF]
, 2020 We formulate a well-posedness and approximation theory for a class of generalised saddle point problems with a specific form of constraints. In this way we develop an approach to a class of fourth order elliptic partial differential equations with point ...
Elliott, Charles M., Herbert, P. J.
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