Results 41 to 50 of about 45,122 (251)
Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Advanced Science, EarlyView.Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Physics of Organelle Membrane Bridging via Cytosolic Tethers is Distinct From Cell Adhesion
Frontiers in Physics, 2022 Tremendous progress has been made recently in imaging the contacts between intra-cellular organelles, which are thought to be mediated by soluble tethers.
Mohammad Arif Kamal +9 more
doaj +1 more source
Extra-matrix Mg\u3csup\u3e2+\u3c/sup\u3e Limits Ca\u3csup\u3e2+\u3c/sup\u3e Uptake and Modulates Ca\u3csup\u3e2+\u3c/sup\u3e Uptake-independent Respiration and Redox State in Cardiac Isolated Mitochondria [PDF]
, 2013 Cardiac mitochondrial matrix (m) free Ca2+ ([Ca2+]m) increases primarily by Ca2+ uptake through the Ca2+ uniporter (CU). Ca2+ uptake via the CU is attenuated by extra-matrix (e) Mg2+ ([Mg2+]e).
Blomeyer, Christoph A. +5 more
core +1 more source
, 2016 Boussinesq-type wave equations involve nonlinearities and dispersion. In this paper a Boussinesq-type equation with amplitude-dependent nonlinearities is presented.
Engelbrecht, Jüri +2 more
core +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Flexible, high‐strength titanium nanowire for scaffold biomimetic periodontal membrane
Biosurface and Biotribology, 2021 A layer of micro‐sized periodontal membrane can buffer most chewing forces to protect the interface between the natural tooth root and alveolar bone. Artificial dental implants usually direct contact onto the alveolar bone without a buffer layer, which ...
Jin Li +5 more
doaj +1 more source
The Influence of Short Motifs on the Anticancer Activity of HB43 Peptide
Pharmaceutics, 2022 Despite the remarkable similarity in amino acid composition, many anticancer peptides (ACPs) display significant differences in terms of activity. This strongly suggests that particular relative dispositions of amino acids (motifs) play a role in the ...
Claudia Herrera-León +9 more
doaj +1 more source
The stability of solitons in biomembranes and nerves [PDF]
, 2005 We examine the stability of a class of solitons, obtained from a generalization of the Boussinesq equation, which have been proposed to be relevant for pulse propagation in biomembranes and nerves.
Heimburg, T. +2 more
core +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Remodeling of Biomembranes and Vesicles by Adhesion of Condensate Droplets
Membranes, 2023 Condensate droplets are formed in aqueous solutions of macromolecules that undergo phase separation into two liquid phases. A well-studied example are solutions of the two polymers PEG and dextran which have been used for a long time in biochemical ...
Reinhard Lipowsky
doaj +1 more source