Results 51 to 60 of about 45,122 (251)

Protein crowding on biomembranes: analysis of contour instabilities

, 2014
Collective behavior of proteins on biomembranes is usually studied within the spontaneous curvature model. Here we consider an alternative phenomenological approach, which accounts consistently for partial ordering of proteins as well as the anchoring ...
Manyuhina, O. V.
core   +1 more source

Active Force Dynamics in Red Blood Cells Under Non‐Invasive Optical Tweezers

Advanced Science, EarlyView.
A non‐invasive method combines low‐power optical tweezers with high‐speed microscopy to simultaneously monitor local membrane forces and displacements in single human red blood cells. This dual‐channel approach reveals a mechano‐dynamic signature that correlates the cell's metabolic state with its mechanical activity. This energetic framework serves as
Arnau Dorn, Clara Luque‐Rioja, Macarena Calero, Diego Herráez‐Aguilar, Francisco Monroy, Niccolò Caselli   +5 more
wiley   +1 more source

Phyto‐fabricated silver nanoparticles inducing microbial cell death via reactive oxygen species‐mediated membrane damage

IET Nanobiotechnology, 2021
Eco‐friendly synthesis of the silver nanoparticles (AgNPs) has a number of advantages like simplicity, biocompatibility, low toxicity in nature over their physical and chemical methods.
L. Srinivas Naik, Ch. Venkata Ramana Devi   +1 more
doaj   +1 more source

The Mechanism of Action of SAAP-148 Antimicrobial Peptide as Studied with NMR and Molecular Dynamics Simulations

Pharmaceutics, 2023
Background: SAAP-148 is an antimicrobial peptide derived from LL-37. It exhibits excellent activity against drug-resistant bacteria and biofilms while resisting degradation in physiological conditions.
Morgane Adélaïde, Evgeniy Salnikov, Francisco Ramos-Martín, Christopher Aisenbrey, Catherine Sarazin, Burkhard Bechinger, Nicola D’Amelio   +6 more
doaj   +1 more source

Model mass spectrometric study of competitive interactions of antimicrobial bisquaternary ammonium drugs and aspirin with membrane phospholipids [PDF]

, 2013
The aim of the study is to reveal molecular mechanisms of possible activity modulation of antimicrobial bis-quaternary ammonium compounds (BQAC) and aspirin (ASP) through noncovalent competitive complexation under their combined introduction into the ...
Gömöry, Ágnes, Kosevich, M. V., Pashynska, V. A., Vékey, Károly   +3 more
core   +2 more sources

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Anti‐inflammatory ethosomal nanoformulation in combination with iontophoresis in chronic wound healing: An ex vivo study

IET Nanobiotechnology, 2021
Prescription of anti‐inflammatory drugs may be considered as a promising strategy in chronic wound healing where the inflammatory disturbance has delayed the healing process.
Reza Mombeiny, Shima Tavakol, Mostafa Kazemi, Mehdi Mehdizadeh, Akbar Hasanzadeh, Mohammad Karimi Babaahmadi, Ali Abedi, Peyman Keyhanvar   +7 more
doaj   +1 more source

Phase transitions in biological membranes

, 2018
Native membranes of biological cells display melting transitions of their lipids at a temperature of 10-20 degrees below body temperature. Such transitions can be observed in various bacterial cells, in nerves, in cancer cells, but also in lung ...
A Blicher, A Blicher, A Gonzalez-Perez, A Gonzalez-Perez, A Hac, A Punnia-Moorthy, AG Lee, AL Hodgkin, AL Hodgkin, B Lautrup, D Johnston, D Papahadjopoulos, DB Mountcastle, DP Kharakoz, E London, EF DeLong, FH Johnson, FH Johnson, GH Kim, GS Manning, H Ebel, H Kamaya, H Kamaya, H Kamaya, H Träuble, HJ Galla, HM Seeger, HM Seeger, I Tasaki, J Gallaher, J Marmur, JE Rothman, JE Rothman, JLCM Vossenberg van de, JM Ritchie, JR Hazel, JR Hazel, JR Trudell, K Græsbøll, K Iwasa, K Iwasa, K Simons, KA Zecchi, KR Laub, L Onsager, LD Mosgaard, LD Mosgaard, LO Ingram, M Gudmand, M Moldovan, MC Sabra, MJ Halsey, MJ Pringle, OG Mouritsen, P Grabitz, PF Almeida, PL Privalov, R Böckmann, R Ravindra, R Winter, RS Cantor, RS Cantor, RW Glaser, S Johnson, SV Avery, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Horishita, Tian Wang, UR Pedersen, Y Kaminoh, Y Zuo   +76 more
core   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source