Results 101 to 110 of about 96,749 (190)

ENGINEERING BIOMOLECULAR CONDENSATES FOR METABOLIC PATHWAY CONTROL

Biomolecular condensates—membrane-less organelles formed through liquid-liquid phase separation—play pivotal roles in cellular biochemistry by organizing processes like ribosome biogenesis, gene expression, and metabolism without membrane boundaries ...
Walls, Mackenzie Thomas
core  

Biomolecular condensates in Hippo pathway regulation

Journal of Zhejiang University-SCIENCE B
Hippo signaling is a highly conserved pathway central to diverse cellular processes. Dysregulation of this pathway not only leads to developmental abnormalities but is also closely related to the occurrence and progression of various cancers. Recent studies have uncovered that, in addition to the classical signaling cascade regulation, biomolecular ...
Yangqing Shao, Yitong Zhang, Wenxuan Zhu, Huasong Lu   +3 more
openaire   +2 more sources

Metal-dependent and metal-free mechanisms of peptide condensate catalysts

Nature Communications
Condensates formed via liquid-liquid phase separation (LLPS) provide a chemically versatile environment for catalysis through dynamic molecular interactions.
Tlalit Massarano, Yuqin Yang, Avigail Baruch Leshem, Ori Eran, Xiaoyu Wang, Hao Dong, Ayala Lampel   +6 more
doaj   +1 more source

Multiphasic condensates formed with mono-component of tetrapeptides via phase separation

Nature Communications
Biomolecular condensates, formed by liquid-liquid phase separation of biomacromolecules, play crucial roles in regulating physiological events in biological systems. While multiphasic condensates have been extensively studied, those derived from a single
Laicheng Zhou, Longchen Zhu, Cong Wang, Tengyan Xu, Jing Wang, Bin Zhang, Xin Zhang, Huaimin Wang   +7 more
doaj   +1 more source

Diffusion of intrinsically disordered proteins within protein condensates

Physical Review Research
Many intrinsically disordered proteins (IDPs) may undergo a phase separation to form a biomolecular condensate. Understanding the behavior of individual molecules within condensates is crucial for characterizing their collective physical properties ...
Fuga Watanabe, Takuma Akimoto, Robert B. Best, Kresten Lindorff-Larsen, Ralf Metzler, Eiji Yamamoto   +5 more
doaj   +1 more source

Current practices in the study of biomolecular condensates: a community comment

International audienceThe realization that the cell is abundantly compartmentalized into biomolecular condensates has opened new opportunities for understanding the physics and chemistry underlying many cellular processes, fundamentally changing the ...
Dimova, Rumiana, Elbaum-Garfinkle, Shana, Rippe, Karsten, Pappu, Rohit, V, Dormann, Dorothee, Vecchiarelli, Anthony, G, Mittal, Jeetain, Mittag, Tanja, Zweckstetter, Markus, Fawzi, Nicolas, L, Lindorff-Larsen, Kresten, Zhang, Mingjie, Best, Robert, B, Dignon, Gregory, L, Jain, Ankur, Zhang, Huaiying, Arosio, Paolo, Gladfelter, Amy, S, Myong, Sua, Cai, Danfeng, Joseph, Jerelle, A, Lasker, Keren, Fuxreiter, Monika, Lipowsky, Reinhard, Collepardo-Guevara, Rosana, Wegmann, Susanne, Knowles, Tuomas, P J, Mukhopadhyay, Samrat, Alberti, Simon, Honigmann, Alf, Lemke, Edward, A, Zubieta, Chloe, Shelkovnikova, Tatyana, A, Boeynaems, Steven   +33 more
core   +1 more source

Insect antiviral Mx-like protein forms biomolecular condensates to promote viral capsid ubiquitinated degradation

Sequence data of paper "Insect antiviral Mx-like protein forms biomolecular condensates to promote viral capsid ubiquitinated degradation" which is published in the journal CELL ...
Li, You
core   +1 more source

Reply to: The conformations of protein chains at the interface of biomolecular condensates

Nature Communications
Gaurav Chauhan, Mina Farag, Samuel R. Cohen, Rohit V. Pappu   +3 more
doaj   +1 more source

The thermodynamic state map of biomolecular condensates. [PDF]

Commun Biol
Hou Y, Jing L, Sun K, Chang Y, Zhao J, Li X, Min J, Wang L.   +7 more
europepmc   +1 more source

Biomolecular Condensates Integrate Transcriptional and Epigenetic Responses to Hypoxia. [PDF]

Int J Mol Sci
Patel CK, Saif A, Ren X.
europepmc   +1 more source