Results 151 to 160 of about 96,749 (190)

Single-particle light scattering reveals structural heterogeneity of biomolecular condensates

Rodríguez BG, Makasewicz K, Tesei G, Eklund F, Johansson E, Arosio P, Volpe G, Midtvedt DS.   +7 more
europepmc   +1 more source

Pharmacologic inhibition of PCBP2 biomolecular condensates relieves Alzheimer's disease. [PDF]

Nat Commun
Wang L, Xie XY, Pan QL, Zhang J, Zhou GF, Zhang QL, Yan XX, Xiang Y, Li CL, He Y, Xiang XJ, Deng XJ, Wang YJ, Zhou JY, Nie S, Chen GJ.   +15 more
europepmc   +1 more source

Biomolecular condensates provide a unique environment for redox-mediated protein crosslinking

Wang H, Favetta B, Wang J, Hoffmann C, Maloku E, Xia Y, Baum J, Milovanovic D, Schuster BS, Shi Z.   +9 more
europepmc   +1 more source

Decoding nucleic acid contributions to phase separation and ordering in biomolecular condensates. [PDF]

Nucleic Acids Res
Asnicar D, Codispoti S, Morasso C, Ferrarini A, Zanchetta G.   +4 more
europepmc   +1 more source

The missing link between biomolecular condensates and amyloid fibrils

Hoti A, Zang S, Prantl E, Grunëwald M, Kros A, Risselada HJ, Sevink GJA.   +6 more
europepmc   +1 more source

Biomolecular Condensates and Cancer [PDF]

Cancer Cell, 2021
Malignant transformation is characterized by dysregulation of diverse cellular processes that have been the subject of detailed genetic, biochemical, and structural studies, but only recently has evidence emerged that many of these processes occur in the
Isaac A Klein, Ann Boija, Richard A. Young   +2 more
exaly   +6 more sources

Biomolecular Condensates: Organizers of Cellular Biochemistry

Nature Reviews Molecular Cell Biology, 2017
Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes but function to concentrate proteins and nucleic acids.
Michael K. Rosen, Hyun O Lee, Anthony Hyman   +2 more
exaly   +2 more sources

Biomolecular Condensates in the Nucleus [PDF]

Trends in Biochemical Sciences, 2020
Nuclear processes such as DNA replication, transcription, and RNA processing each depend on the concerted action of many different protein and RNA molecules. How biomolecules with shared functions find their way to specific locations has been assumed to occur largely by diffusion-mediated collisions.
Alessandra Dall'Agnese, Benjamin R Sabari, Richard A. Young   +2 more
exaly   +4 more sources

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Biophysics of biomolecular condensates

Biophysical Journal, 2023
The formation of biomolecular condensates has emerged as a new biophysical principle for subcellular compartmentalization within cells to facilitate the spatiotemporal regulation of a multitude of complex biomolecular reactions. In this Research Highlight, we summarize the findings that were published in Biophysical Journal during the past two years ...
Ashish, Joshi, Samrat, Mukhopadhyay
openaire   +2 more sources

Biomolecular condensates in epithelial junctions

Current Opinion in Cell Biology, 2022
Epithelial junctions are transmembrane protein complexes that regulate cell adhesion, cell polarity, tissue permeability, and tissue mechanics. Most junctional complexes contain membrane attached cytoplasmic plaques that regulate junction assembly and are composed of multivalent scaffold proteins.
Sun, D., LuValle-Burke, I., Pombo-García, K., Honigmann, A.   +3 more
openaire   +3 more sources