Results 151 to 160 of about 101,810 (380)

Challenges of developing decision-support LCA tools in the biopharmaceutical industry [PDF]

, 2013
The biopharmaceutical industry has been slow in carrying out LCA analyses. However, as the industry matures, the level of scrutiny placed on this industry by international governments will increase and hence, there is an urgent need for the industry to ...
Lettieri, P, Ramasamy, S, Titchener-Hooker, N   +2 more
core  

Over‐Expression of a Phycocyanin‐Interferon Fusion and Differential Cleaving Efficiency in Cyanobacteria (Synechocystis sp. PCC 6803)

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Recombinant protein expression in heterologous biological systems is an expanding field in synthetic biology. Photosynthetic organisms have the potential to provide an efficient low‐cost platform for recombinant protein production because they require minimal growth nutrients and are less susceptible to zoonotic and other contaminants ...
Bharat Kumar Majhi, Anastasios Melis
wiley   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source

Simple and High-Throughput Quantification of Mono- and Bivalent Foot-and-Mouth Disease Virus Vaccine Antigens by Differential Scanning Fluorimetry

Vaccines
Background/Objectives: An accurate quantification of the effective antigens from different serotypes is essential for the quality control of multivalent vaccines, but it remains challenging.
Yanli Yang, Xiaojie Chen, Ming Li, Fei Xin, Yi Zhao, Chengfeng Zhang, Yiping Pan, Chuanyu He, Sun He   +8 more
doaj   +1 more source

Non-invasive spectroscopic methods for single-vial PAT in biopharmaceutical freeze-drying. On-line presentation at Marcus Evans 12th Biologics Formulation Development & Drug Delivery Forum June 14-15th 2021

, 2021
Geoffrey Smith
openalex   +2 more sources

Refolding in the modern biopharmaceutical industry.

Biotechnology Advances, 2022
Luisa Buscajoni, Michael C. Martinetz, M. Berkemeyer, C. Brocard   +3 more
semanticscholar   +1 more source

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

Biotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse, Fabian Schmitz, Janina Kilian, Jonas Austerjost, Lucas‐Nik Reger, Markus Kampmann   +5 more
wiley   +1 more source

Editorial: Proceedings of ISPMF 2018 - Plant Molecular Farming

Frontiers in Plant Science, 2020
Anneli Ritala, Heiko Rischer, Suvi Tuulikki Häkkinen, Jussi Joonas Joensuu, Kirsi-Marja Oksman-Caldentey   +4 more
doaj   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

A questionnaire-based study on industrial waste management in Indian biopharmaceutical industries

Environment Conservation Journal
This study investigates industrial waste management practices within the Indian biopharmaceutical sector through a questionnaire-based approach. The questionnaire, distributed among ten Indian biopharmaceutical industries (Himachal Pradesh (30°57'26.3"
Ishika Pringle, Navjeevan Dadwal, Arun Kumar   +2 more
doaj   +1 more source