Results 161 to 170 of about 39,175 (290)

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

ESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal, Macarena P. Quintana‐Hayashi, Kathleen Connolly, Daniel Pettersen, Zsolt Cselényi, Aurelija Jucaite, Magnus Schou, Andrea Varrone, Melanie Chan, Lars H. Lund   +9 more
wiley   +1 more source

Textbook of Biopharmaceutic Analysis

, 1982
Karl H. Schram
openalex   +1 more source

Galectin‐3 and kidney function in type 2 diabetes treated with dapagliflozin: Analysis from DECLARE‐TIMI 58

ESC Heart Failure, EarlyView.
Abstract Background Galectin‐3 (Gal‐3) is a circulating biomarker of fibrosis, with higher levels being associated with an increased risk of progression of heart failure and kidney disease. Patients with type 2 diabetes mellitus (T2DM) are at increased risk of both.
Paul M. Haller, Stephen D. Wiviott, David D. Berg, Petr Jarolim, Erica L. Goodrich, Deepak L. Bhatt, Ingrid Gause‐Nilsson, Lawrence A. Leiter, Darren K. McGuire, John P.H. Wilding, Itamar Raz, Marc S. Sabatine, David A. Morrow   +12 more
wiley   +1 more source

Biopharmaceutical Studies of Drugs. II. The Competitive Inhibition of Pentazocine Glucuronidation by Salicylamide in Vitro

, 1980
KAZUO KIGASAWA, Hiroaki Shimizu, Morihiro Saito, Toshihiro Hayashi   +3 more
openalex   +2 more sources

Recent developments in the use of transgenic plants for the production of human therapeutics and biopharmaceuticals [PDF]

, 2004
N. P. Teli, Michael P. Timko
openalex   +1 more source

Management of patients with heart failure at high risk of hyperkalaemia: The CARE‐HK in HF registry

European Journal of Heart Failure, EarlyView.
Primary results of the CARE‐HK in HF registry. ACEI, angiotensin‐converting enzyme inhibitor; ARB, angiotensin II receptor blocker; ARNI, angiotensin receptor–neprilysin inhibitor; CI, confidence interval; eGFR, estimated glomerular filtration rate; HF, heart failure; HK, hyperkalaemia; HR, hazard ratio; MRA, mineralocorticoid receptor antagonist; RASi,
Stephen J. Greene, Andrew J. Sauer, Michael Böhm, Biykem Bozkurt, Javed Butler, John G.F. Cleland, Andrew J.S. Coats, Nihar R. Desai, Diederick E. Grobbee, Ellie Kelepouris, Fausto Pinto, Giuseppe Rosano, Victoria Donachie, Solenn Fabien, Sandra Waechter, Maria G. Crespo‐Leiro, Martin Hülsmann, Tibor Kempf, Otmar Pfister, Anne‐Catherine Pouleur, Manish Saxena, Martin Schulz, Maurizio Volterrani, Stefan D. Anker, Mikhail N. Kosiborod   +24 more
wiley   +1 more source

Control of biopharmaceutical properties of uricase by conjugation with dextran derivatives.

, 1989
Yoshinobu Takakura, Takuya Fujita, Yoshihisa Yasuda, Mitsuru Hashida, Hitoshi Sezaki   +4 more
openalex   +2 more sources

Characteristics of the late-stage biopharmaceutical pipeline [PDF]

, 2004
Paul P Nagle, Timothy F Lugo, Christopher A Nicita   +2 more
openalex   +1 more source

Global patterns of polypharmacy after acute heart failure hospitalization: Prevalence and outcomes from the REPORT‐HF registry

European Journal of Heart Failure, EarlyView.
Global patterns of polypharmacy after acute heart failure hospitalization. GDMT, guideline‐directed medical therapy; HF, heart failure. Aims Polypharmacy, defined as the concurrent use of ≥5 medications, is prevalent among older adults with heart failure (HF).
Wan Ting Tay, Tiew‐Hwa Katherine Teng, Wouter Ouwerkerk, John G.F. Cleland, Sean P. Collins, Christiane E. Angermann, Kenneth Dickstein, Ulf Dahlstrom, Anja Schweizer, Achim Obergfell, Kai‐Hang Yiu, Mathieu Ghadanfar, Mahmoud Hassanein, Qing‐Wen Ren, Wen‐Li Gu, Georg Ertl, Sergio V. Perrone, Gerasimos Filippatos, Carolyn S.P. Lam, Jasper Tromp   +19 more
wiley   +1 more source

Expression of concern: Flavin-adenine-dinucleotide gold complex nanoparticles: chemical modeling design, physico-chemical assessment and perspectives in nanomedicine. [PDF]

Nanoscale Adv
Arib C, Bouchemal N, Barile M, Paleni D, Djaker N, Dupont N, Spadavecchia J.   +6 more
europepmc   +1 more source