Results 181 to 190 of about 32,871 (300)

The Pain in Dystonia Scale (PIDS)—Validation in Craniofacial and Upper Limb Dystonia

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Pain is one of the most disabling non‐motor symptoms in adult‐onset isolated dystonia (AOID). The Pain in Dystonia Scale (PIDS) was developed and validated in cervical dystonia. Its applicability to other focal subtypes remains unknown.
Veronica Bruno, Vittorio Velucci, Beatrice Achen, Marcello Mario Mascia, Antonella Muroni, Daniele Belvisi, Francesco Marchet, Laura Avanzino, Francesca Di Biasio, Roberto Erro, Cristiano Sorrentino, Lucio Marinelli, Flavio Villani, Antonio Pisani, Francesca Valentino, Angelo Fabio Gigante, Anna Castagna, Francesco Bono, Giovanni Cossu, Carlo Alberto Artusi, Carmen Terranova, Martina Petracca, Nicola Tambasco, Giovanni Defazio, Davide Martino   +24 more
wiley   +1 more source

Correction: Meta-analysis of the efficiency and safety of neoadjuvant therapy with immune checkpoint inhibitors in resectable hepatocellular carcinoma. [PDF]

Front Med (Lausanne)
Frontiers Production Office.
europepmc   +1 more source

Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha‐Synuclein Seed Amplification Assay

Movement Disorders, EarlyView.
Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker, Jacopo Pasquini, Seung Ho Choi, David‐Erick Lafontant, Seyed‐Mohammad Fereshtehnejad, Yashar Zeighami, Piergiorgio Grillo, Giulietta M. Riboldi, Houman Azizi, Roqaie Moqadam, Un Jung Kang, Kelly N.H. Nudelman, Andrew Siderowf, Caroline M. Tanner, Thomas F. Tropea, Tatiana Foroud, Lana M. Chahine, Brit Mollenhauer, Kalpana M. Merchant, Douglas Galasko, Christopher S. Coffey, Roseanne D. Dobkin, Ethan G. Brown, Roy N. Alcalay, Daniel Weintraub, Kenneth Marek, Tanya Simuni, Paulina Gonzalez‐Latapi, Nicola Pavese, Kathleen L. Poston, the Parkinson's Progression Markers Initiative   +30 more
wiley   +1 more source

Virtual Bioequivalence Assessment and Dissolution Safe Space Exploration for Fixed-Dose Metformin-Glyburide Tablet Using Physiologically Based Biopharmaceutics Modeling. [PDF]

Pharmaceutics
Zhao C, Shen C, Xiao Y, Wang L.
europepmc   +1 more source

Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers

Movement Disorders, EarlyView.
Abstract Background GBA1 encodes the lysosomal enzyme glucocerebrosidase, with key substrates that include glucosylceramide and glucosylsphingosine. The E365K variant is the most common variant in GBA1 that is associated with Parkinson's disease (PD) but is not associated with Gaucher disease.
Julian Agin‐Liebes, Alexander Haimovich, Rachel Griep, Nathan Galen Hatcher, Lihang Yao, Cheryl Waters, Shalini Padmanabhan, Roy N. Alcalay   +7 more
wiley   +1 more source

Editorial: Role of nanocarriers and non-coding RNAs in solid malignancies. [PDF]

Front Oncol
Youness RA, Fahmy SA, Efthimiadou EK, Braoudaki M, Rashid G.   +4 more
europepmc   +1 more source

Machine Learning‐Driven Predictive Modeling and Multi‐Objective Exploration of Oxaliplatin‐Loaded Nanocarriers for Enhanced Loading and Encapsulation Efficiency

Materials Genome Engineering Advances, EarlyView.
Integrating ML and multi‐objective optimization enabled efficient, accurate design of nanocarriers with optimized loading and encapsulation efficiencies. ABSTRACT Oxaliplatin (OXA), a critical third‐generation platinum chemotherapeutic, is significantly limited by suboptimal loading capacity and encapsulation efficiency in nanoparticle‐based delivery ...
Abbas Rahdar, Maryam Shirzad, Sonia Fathi‐Karkan, M. Ali Aboudzadeh   +3 more
wiley   +1 more source

Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers. [PDF]

Nucleic Acids Res
Lu Z, Sun H, Fu B, Ao Y, Wang J, Chen K, Luo Y, Li L, Qiu Z, Zhao J, Sun Y, Tan Z, Liu Q, Ren Y, Guo Z, Chen X, He Y, Zhao Y, Chen Y, Li M, Peng X, Huang B, Zhu S, Huang L, Miao Z.   +24 more
europepmc   +1 more source

Biopharmaceutics, Pharmacy and Pharmacology [PDF]

, 2004
片山 和憲, 登美 斉俊, 細谷 健一   +2 more
core   +1 more source

Parallel Analysis of Acidic and Basic Proteoforms in Cell Lysates via Native Cation and Anion Exchange Chromatography—Native Mass Spectrometry

PROTEOMICS, EarlyView.
ABSTRACT Comprehensive characterization of proteoforms in complex biological systems remains a significant challenge. While native ion‐exchange chromatography (IEC) hyphenated with native mass spectrometry (nMS) is a powerful tool for resolving proteoforms, three critical limitations persist: restricted volatile buffers causing nonlinear pH gradients ...
Ziran Zhai, Hafsa Zakri, Matteo Damian, Francesco G. Mutti, Garry Corthals, Andrea F. G. Gargano   +5 more
wiley   +1 more source