Results 191 to 200 of about 32,871 (300)

Editorial: Immune checkpoints regulatory mechanisms and immunotherapy strategies in gastrointestinal tumors. [PDF]

Front Oncol
Xi Q, Zhang R.
europepmc   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Corrigendum to "Repeat application of microneedles does not alter skin appearance or barrier function and causes no measurable disturbance of serum biomarkers of infection, inflammation or immunity in mice in vivo" [Eur. J. Pharm. Biopharm. 117 (2017) 400-407].

Eur J Pharm Biopharm
Vicente-Perez EM, Larrañeta E, McCrudden MTC, Kissenpfennig A, Hegarty S, McCarthy HO, Donnelly RF.   +6 more
europepmc   +1 more source

Biopharmaceutics, Pharmacy and Pharmacology [PDF]

, 2006
登美 斉俊, 立川 正憲, 細谷 健一   +2 more
core   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina, Stefan Franzén, Maria C. Kjellsson   +2 more
wiley   +1 more source

SLC52A1 is a neofunctionalized primate urate transporter enabling intestinal urate secretion. [PDF]

J Biol Chem
Yamamoto S, Inoue K, Yasujima T, Takei H, Yamashiro T, Asai K, Matake I, Uchiyama S, Ohta K, Kishimoto H, Higuchi K, Anayama H, Asao Y, Hirabayashi H, Amano N, Shimizu T, Takada T, Tamura T, Wakai K, Kawamura Y, Nakayama A, Toyoda Y, Matsuo H, Yuasa H.   +23 more
europepmc   +1 more source

Structure and functional genes associated with carbon, nitrogen, phosphorus, and sulfur cycling processes in periphyton: A comparison between natural and artificial rivers

River, EarlyView.
Network analysis of functional genes among prokaryotes, and eukaryotes in natural and artificial rivers. Abstract Periphyton in aquatic ecosystems plays vital roles in the elemental cycle process and is vulnerable to anthropogenic interference. However, few studies have explored the elemental cycles of carbon (C), nitrogen (N), phosphorus (P), and ...
Yulu Tian, Jiezhang Mo, Jiaxin Liu, Chenghao Li, Jiahua Guo   +4 more
wiley   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

Small, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira, Hiroshi Kamizawa, Yujiro Hamada, Wataru Fushimoto, Hiroshi Y. Yoshikawa, Yuji Higaki, Atsushi Takahara, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura   +9 more
wiley   +1 more source

Reprogramming Imine Reductases for Enantioselective Reduction of Electron-Rich Enamides. [PDF]

JACS Au
Liu XQ, Li R, Chen JL, Li Y, Wei L, Wu H, Li L, Chen BH, Wu Y, Liu SJ, Lin GX, Zhang JF, Zheng Y, Zhang C, Yang YF, Wang X, Chen P, Jia ZJ.   +17 more
europepmc   +1 more source

Indocyanine Green–Inspired Polymeric Chromophores With Intrinsic Photostability for Near‐Infrared Imaging

Small, EarlyView.
Indocyanine green (ICG) is widely used for near‐infrared imaging but suffers from poor photostability. Here, an indocyanine green–inspired polymeric NIR chromophore is introduced, exhibiting intrinsically enhanced photostability and biocompatibility.
Su Bin Lee, Minsuk Choi, Young Hoon Son, Minseo Kim, Hye Sun Park, Seung Hyeon Kim, Ogabek Oybek Ugli Juraev, Hyocheol Jung, Hyoung Eun Bae, Ji‐Eun Jeong, Young‐Jae Jin, Jin Chul Kim, Sung‐Jin Park, Sang Hwan Nam, Young Il Park   +14 more
wiley   +1 more source