Results 191 to 200 of about 10,064 (258)

Development of a Physiologically Based Biopharmaceutics Model Report Template: Considerations for Improved Quality in View of Regulatory Submissions. [PDF]

Mol Pharm
Arora S, Pepin X, Jamei M, Sharma P, Heimbach T, Wagner C, Bransford P, Kollipara S, Ahmed T, Hingle M, Dallmann A, Scherholz M, Stamatis SD, Cano-Vega M, Mistry N, Tannergren C, Borges L, Lindahl A, Rullo G, Mackie C, Mitra A, Kushner J, Harish Jain KM, Polli JE.   +23 more
europepmc   +1 more source

Situated Attention and Strategic Leadership Interfaces: The Role of CEO Humility and Digital Transformation Urgency for Corporate Venture Capital Investments

Journal of Management Studies, EarlyView.
Abstract Integrating the attention‐based view with the strategic leadership interfaces perspective, we propose a theoretical model of situational urgency mechanisms influencing the allocation of CEOs' attention towards responsive actions. Specifically, we theorize upon the role of humility, which leads CEOs towards embracing interfaces and makes them ...
Petrit Ademi, Philipp Schade, Monika C. Schuhmacher   +2 more
wiley   +1 more source

Association of <i>ABCB1</i> Genetic Variants with Epilepsy Susceptibility in Jordanian Cohort. [PDF]

Neurol Int
Abduljabbar R, Yousef AM, Eid Tamimi D, Z Abdullah S, Liu Z.   +4 more
europepmc   +1 more source

Whom Should Entrepreneurs Approach? The Effect of Contact Status on Referring New Ventures for Acquisition

Journal of Management Studies, EarlyView.
Abstract Prior entrepreneurial network literature has primarily examined how entrepreneurs’ networking efforts facilitate interorganizational exchanges, while giving little attention to the agency of their contacts. In this study, we investigate how contacts’ intra‐organizational status shapes their actions of referring entrepreneurs to their ...
Xi Chen, Jiaosha Chen, Jin Chen, Ruining Cao   +3 more
wiley   +1 more source

Biowaiver monograph for immediate-release solid oral dosage forms: Empagliflozin. [PDF]

J Pharm Sci
Negoya R, Tsueoka M, Sun X, Nishida S, Abrahamsson B, Charoo NA, Cristofoletti R, Langguth P, Mehta M, Parr A, Polli JE, Shah VP, Dressman J, Kambayashi A.   +13 more
europepmc   +1 more source

Polyphenol oxidase depletion in Nicotiana benthamiana enhances recombinant protein purification and preserves native protein integrity

New Phytologist, EarlyView.
Polyphenol oxidases (PPOs) depletion preserves endogenous proteins at their predicted molecular weights and enhances detectable enzymatic activities. (a) Less RbcL crosslinking in ppo mutant of Nicotiana benthamiana. Leaf extracts were incubated for 1 h, separated on protein gels, stained with Coomassie or analyzed by Western blot with the anti‐RbcL ...
Kaijie Zheng, Farnusch Kaschani, Emma C. Watts, Markus Kaiser, Renier A. L. van der Hoorn   +4 more
wiley   +1 more source

Budget impact analysis of the introduction of ranibizumab's biosimilar to the Jordanian joint procurement system. [PDF]

Front Public Health
Hamida JA, Alkhatib NS, Hammour KA, Halloush S, Kurdi A, Balkhi B, Alfayez OM, Mousa R.   +7 more
europepmc   +1 more source

Harnessing Bulk‐Segregant Mapping to Identify Trait‐Associated Genes in the Allopolyploid Model Plant Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Forward genetics has been instrumental in identifying genes underlying desirable traits, yet its application to polyploid plants, many of which are key agricultural crops, remains challenging due to their genomic complexity. Therefore, we developed BenthMap, a bulk segregant analysis platform for high‐throughput trait mapping and gene ...
Zuba Ahmed, Jiyuan An, Satomi Hayashi, Julia Bally, Chris Winefield, Peter M. Waterhouse   +5 more
wiley   +1 more source

Overcoming Immunotolerance in Chronic Hepatitis B: Efficacy of Granulocyte-Macrophage Colony-Stimulating Factor-Based Immunotherapy in Achieving Hepatitis B Surface Antigen Seroclearance. [PDF]

MedComm (2020)
Geng S, Yang F, Jia H, Zhao G, Zhao W, Yu J, Zhu H, Cai H, Yang L, Zhang S, Yu F, Jin X, Zhang S, Wang X, Yang Y, Zhang J, Wang B.   +16 more
europepmc   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, EarlyView.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source