Results 211 to 220 of about 10,064 (258)
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The immunogenicity of biopharmaceuticals
Neurology, 2003The medical use of proteins has a long history. It started more than one century ago when immune sera of animal origin were introduced for the prevention or treatment of infections, followed by the use of insulin of porcine and bovine origin some decades later.
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On the acceptability of biopharmaceuticals
Science and Engineering Ethics, 1996The issues relating to the licensing of a biopharmaceutical are described. In particular attention is focused on the mind of the regulator who has the responsibility of recommending licensure. There are two key factors which operate on the mind when confronted with such a task: psychology and ethics.
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Current Opinion in Biotechnology, 2000
The rapid maturation of the field of biopharmaceutical formulation is the result of the simultaneous development of a thermodynamic mechanism for protein-solvent interaction and identification of natural chemicals employed by nature to stabilize proteins in response to environmental stresses.
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The rapid maturation of the field of biopharmaceutical formulation is the result of the simultaneous development of a thermodynamic mechanism for protein-solvent interaction and identification of natural chemicals employed by nature to stabilize proteins in response to environmental stresses.
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Introduction. Biopharmaceutics and Pharmacokinetics
2018Biopharmaceutics and pharmacokinetics are pharmaceutical disciplines useful to improve the outcome of drug therapies, assist drug product development, and establish pharmacokinetics-pharmacodynamics models and in vitro-in vivo correlations. Here, we introduce some essential lexicon that will be used throughout this volume and discuss the relationship ...
Talevi, Alan, Quiroga, Pablo A. M.
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2015
Biopharmaceutics is the field that investigates and describes everything that happens with a medicinal product and the active substance between the moment of administration, the moment it exerts its action and the moment it is eliminated from the body. Biopharmaceutics connects the physico-chemical properties of an active substance and its dosage form ...
Frijlink, Erik +2 more
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Biopharmaceutics is the field that investigates and describes everything that happens with a medicinal product and the active substance between the moment of administration, the moment it exerts its action and the moment it is eliminated from the body. Biopharmaceutics connects the physico-chemical properties of an active substance and its dosage form ...
Frijlink, Erik +2 more
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2017
Biopharmaceuticals are primarily therapeutic proteins developed to perform specific functions by acting on the disease pathophysiology. Compared with low-molecular chemically synthesized drugs, production of biopharmaceuticals is much more complex and routes of administration and pharmacokinetics differ.
Gils, Ann +4 more
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Biopharmaceuticals are primarily therapeutic proteins developed to perform specific functions by acting on the disease pathophysiology. Compared with low-molecular chemically synthesized drugs, production of biopharmaceuticals is much more complex and routes of administration and pharmacokinetics differ.
Gils, Ann +4 more
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Biopharmaceutical benchmarks 2006
Nature Biotechnology, 2006The rate of biopharmaceutical approvals has leveled off, but some milestones bode well for the future.
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Biopharmaceutical benchmarks 2010
Nature Biotechnology, 2010Over the past four years, several new types of experimental biologic treatment have received commercial registration, but the emergence of biosimilars represents the biggest shift in the biologic approval landscape.
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