Results 211 to 220 of about 32,871 (300)

Power priors for latent variable mediation models under small sample sizes

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Latent variable models typically require large sample sizes for acceptable efficiency and reliable convergence. Appropriate informative priors are often required for gainfully employing Bayesian analysis with small samples. Power priors are informative priors built on historical data, weighted to account for non‐exchangeability with the ...
Lihan Chen, Milica Miočević, Carl F. Falk   +2 more
wiley   +1 more source

Biowaiver monograph for immediate-release solid oral dosage forms: Empagliflozin. [PDF]

J Pharm Sci
Negoya R, Tsueoka M, Sun X, Nishida S, Abrahamsson B, Charoo NA, Cristofoletti R, Langguth P, Mehta M, Parr A, Polli JE, Shah VP, Dressman J, Kambayashi A.   +13 more
europepmc   +1 more source

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Overcoming Immunotolerance in Chronic Hepatitis B: Efficacy of Granulocyte-Macrophage Colony-Stimulating Factor-Based Immunotherapy in Achieving Hepatitis B Surface Antigen Seroclearance. [PDF]

MedComm (2020)
Geng S, Yang F, Jia H, Zhao G, Zhao W, Yu J, Zhu H, Cai H, Yang L, Zhang S, Yu F, Jin X, Zhang S, Wang X, Yang Y, Zhang J, Wang B.   +16 more
europepmc   +1 more source

The rise of AI in healthcare education: DeepSeek and GPT-4o take on the 2024 Taiwan Pharmacist Exam. [PDF]

J Chin Med Assoc
Wang YM, Chen TJ.
europepmc   +1 more source

Biopharmaceutic

Journal of Pharmacy and Pharmacology, 2006
openaire   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Bioequivalence centres in Africa: current state and opportunities for growth. [PDF]

J Pharm Policy Pract
Ncube BM, Muthuri S, Ajose O, Kikwai L.
europepmc   +1 more source

Glycemic Variability Bridges Time in Range and Time in Tight Range: A Unified Equation for Both Type 1 and Type 2 Diabetes Based on Large‐Scale Continuous Glucose Monitoring Data

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to establish a regression model for the relationship between time in range (TIR) and time in tight range (TITR) in individuals with type 1 diabetes (T1D) and type 2 diabetes (T2D) based on real‐world continuous glucose monitoring (CGM) data.
Yuan Yao, Zhigang Hu, Yifei Mo, Mingsong Han, Li Cao, Jinghao Cai, Xiaojing Ma, Jingyi Lu, Xiaobing Wu, Jian Zhou   +9 more
wiley   +1 more source

Integrating In Vitro BE Checker with In Silico Physiologically Based Biopharmaceutics Modeling to Predict the Pharmacokinetic Profiles of Oral Drug Products. [PDF]

Pharmaceutics
Niino T, Masada T, Takagi T, Kataoka M, Yoshida H, Yamashita S, Kambayashi A.   +6 more
europepmc   +1 more source