Results 211 to 220 of about 39,175 (290)

Physiologically-Based Biopharmaceutics Modeling for Ibuprofen: Identifying Key Formulation Parameter and Virtual Bioequivalence Assessment. [PDF]

open access: yesPharmaceutics
Zarzoso-Foj J   +5 more
europepmc   +1 more source

Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry [PDF]

open access: green, 2009
Igor A. Kaltashov   +4 more
openalex   +1 more source

Development of a step‐gradient simulated moving bed process for the polishing of monoclonal antibodies with anion exchange chromatography

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND In recent years, biopharmaceutical applications in medicine have seen explosive growth and the need for efficient, rapid and inexpensive purification of these targets is the topic of tremendous research and development. The need to improve process efficiency has been an active area of investigation due to the tremendous potential ...
Yasmina MJ Harsy   +5 more
wiley   +1 more source

A significant number of pediatric inflammatory bowel disease patients are exposed to a medication not approved by the Food and Drug Administration for pediatric use

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) presents before age 20 years in ~25% of patients. Regulatory approvals of IBD medications for pediatric use are often delayed. Nevertheless, many pediatric patients receive medication not approved for pediatric use.
Courtney Rusch   +3 more
wiley   +1 more source

Autoencoding Raman Spectra to Predict Analyte Concentrations

open access: yesJournal of Raman Spectroscopy, EarlyView.
An autoencoder‐based machine learning regression model was developed using datasets from nuclear and biopharmaceutical industries, utilising spatial heterodyne spectrometers under spontaneous and resonance conditions. This study focuses on the impact of small data volumes on data augmentation and architecture designs.
Alex Poppe   +4 more
wiley   +1 more source

Corrigendum to 'Enhanced sclerotherapy for vascular malformations: A dual-mechanism approach using in-situ forming PATDs gel' [Mater. Today Bio 29 (2024) 101376]. [PDF]

open access: yesMater Today Bio
Ma J   +14 more
europepmc   +1 more source

Kinetics and Thermodynamics of Tautomerization Reactions of 1,1‐ and 1,2‐Ethenediols

open access: yesInternational Journal of Chemical Kinetics, EarlyView.
ABSTRACT Tautomerism is a common phenomenon amongst organic molecules with easily interconvertible isomers, which can impact drug action and toxicity. Here we are interested in the enols of carboxylic acids, which are known to be much less stable than their acid counterparts.
Judith Würmel, John M. Simmie
wiley   +1 more source

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