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Comparing Multi-Label Classification Methods for Provisional Biopharmaceutics Class Prediction. [PDF]
, 2014 The biopharmaceutical classification system (BCS) is now well established and utilized for the development and biowaivers of immediate oral dosage forms. The prediction of BCS class can be carried out using multilabel classification.
Taravat Ghafourian +8 more
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Physiologically based biopharmaceutics modeling of regional and colon absorption in humans
, 2023 Colon absorption is a key determinant for successful development of extended release and colon targeted drug products. This is the first systematic evaluation of the ability to predict in vivo regional differences in absorption and the extent of colon ...
Jadhav, Harshad +11 more
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Microbiology Spectrum, 2014 ABSTRACTPlasmids are currently an indispensable molecular tool in life science research and a central asset for the modern biotechnology industry, supporting its mission to produce pharmaceutical proteins, antibodies, vaccines, industrial enzymes, and molecular diagnostics, to name a few key products.
Duarte Miguel F, Prazeres +1 more
openaire +2 more sources
Pharmaceutics, 2023 Medical practitioners commonly use oral and parenteral dosage forms to administer drugs to patients. However, these forms have certain drawbacks, particularly concerning patients’ comfort and compliance.
Avelia Devina Calista Nainggolan +5 more
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, 2022 S.257-272Over the years, a wide variety of nanomedicines has entered global markets, providing a blueprint for the emerging generics industry. They are characterized by a unique pharmacokinetic behavior difficult to explain with conventional methods.
Modh, H. +7 more
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Bioethical issues in the development of biopharmaceuticals [PDF]
Filozofija i Društvo, 2012 Development of biopharmaceuticals is a challenging issue in bioethics. Unlike conventional, small molecular weight drugs, biopharmaceuticals are proteins derived from DNA technology and hybrid techniques with complex three dimensional structures ...
Todorović Zoran, Protić Dragana
doaj +1 more source
Pharmaceutics, 2020 Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class.
Milica Markovic +4 more
doaj +1 more source
Subcutaneous Biopharmaceutics: Building tools for a flexible future
British Journal of Pharmacy, 2023 The major biopharmaceutics challenge faced during the development of subcutaneous (SC) drug products is the limited understanding of the physiological factors and the combination product attributes that can impact absorption rate/extent and drug product ...
Kate Louise Harris +4 more
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Metal-organic frameworks for advanced drug delivery
Acta Pharmaceutica Sinica B, 2021 Metal-organic frameworks (MOFs), comprised of organic ligands and metal ions/metal clusters via coordinative bonds are highly porous, crystalline materials.
Siyu He +11 more
doaj +1 more source
Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products
Pharmaceutics, 2020 Prodrugs are bioreversible, inactive drug derivatives, which have the ability to convert into a parent drug in the body. In the past, prodrugs were used as a last option; however, nowadays, prodrugs are considered already in the early stages of drug ...
Milica Markovic +2 more
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