Results 21 to 30 of about 10,035 (161)
, 2023 Biopharmaceutics, in connection with pharmacokinetics, is the field that investigates and describes everything that happens with a medicinal product and the active substance between the moment of administration, the moment it exerts its action and the moment it is eliminated from the body. Biopharmaceutics connects the physico-chemical properties of an
Frijlink, Henderik +3 more
openaire +3 more sources
Bioethical issues in the development of biopharmaceuticals [PDF]
Filozofija i Društvo, 2012 Development of biopharmaceuticals is a challenging issue in bioethics. Unlike conventional, small molecular weight drugs, biopharmaceuticals are proteins derived from DNA technology and hybrid techniques with complex three dimensional structures ...
Todorović Zoran, Protić Dragana
doaj +1 more source
Pharmaceutics, 2020 Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class.
Milica Markovic +4 more
doaj +1 more source
Subcutaneous Biopharmaceutics: Building tools for a flexible future
British Journal of Pharmacy, 2023 The major biopharmaceutics challenge faced during the development of subcutaneous (SC) drug products is the limited understanding of the physiological factors and the combination product attributes that can impact absorption rate/extent and drug product ...
Kate Louise Harris +4 more
doaj +1 more source
Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products
Pharmaceutics, 2020 Prodrugs are bioreversible, inactive drug derivatives, which have the ability to convert into a parent drug in the body. In the past, prodrugs were used as a last option; however, nowadays, prodrugs are considered already in the early stages of drug ...
Milica Markovic +2 more
doaj +1 more source
Metal-organic frameworks for advanced drug delivery
Acta Pharmaceutica Sinica B, 2021 Metal-organic frameworks (MOFs), comprised of organic ligands and metal ions/metal clusters via coordinative bonds are highly porous, crystalline materials.
Siyu He +11 more
doaj +1 more source
Nanomaterials, 2018 (1) Background: There is a growing need for the development of new methods for the synthesis of nanoparticles. The interest in such particles has raised concerns about the environmental safety of their production methods; (2) Objectives: The current ...
Alaa A. A. Aljabali +8 more
doaj +1 more source
Vaccines, 2023 Waves of breakthrough infections by SARS-CoV-2 Omicron subvariants currently pose a global challenge to the control of the COVID-19 pandemic. We previously reported a pVAX1-based DNA vaccine candidate, pAD1002, that encodes a receptor-binding domain (RBD)
Yuan Ding +8 more
doaj +1 more source
Vaccines, 2023 The SARS-CoV-2 pandemic remains an ongoing threat to global health with emerging variants, especially the Omicron variant and its sub-lineages. Although large-scale vaccination worldwide has delivered outstanding achievements for COVID-19 prevention, a ...
Gan Zhao +10 more
doaj +1 more source
AMB Express, 2021 Gordonia sp. are members of the actinomycete family, their contribution to the environment improvement and environmental protection by their biological degradation ability, but there are few studies on the antimicrobial activity of their secondary ...
Yan Ma +6 more
doaj +1 more source