Results 11 to 20 of about 10,035 (161)

Diammonium Glycyrrhizinate-Based Micelles for Improving the Hepatoprotective Effect of Baicalin: Characterization and Biopharmaceutical Study

open access: yesPharmaceutics, 2022
Saponins are an important class of surface-active substances. When formulated as an active ingredient or co-used with other drugs, the effect of their surface activity on efficacy or safety must be considered.
Xingxing Dai   +11 more
doaj   +1 more source

Advanced and Innovative Nano-Systems for Anticancer Targeted Drug Delivery

open access: yesPharmaceutics, 2021
The encapsulation of therapeutic agents into nano-based drug delivery system for cancer treatment has received considerable attention in recent years. Advancements in nanotechnology provide an opportunity for efficient delivery of anticancer drugs.
Lu Tang   +5 more
doaj   +1 more source

Immunogenicity of biopharmaceuticals [PDF]

open access: yesNephrology Dialysis Transplantation, 2006
The availability of biopharmaceuticals has been increasing over the past decade and as their patents expire, the emergence of biosimilar agents approaches. The primary issue of concern for the safety of these agents is the potential for immunogenicity.
Michele, Kessler   +2 more
openaire   +2 more sources

New insight into the importance of formulation variables on parenteral growth hormone preparations: potential effect on the injection-site pain

open access: yesFrontiers in Endocrinology, 2022
Reducing injection-site pain (ISP) in patients with chronic conditions such as growth hormone deficiency is a valuable strategy to improve patient compliance and therapeutic efficiency.
Bita Taghizadeh   +4 more
doaj   +1 more source

Understanding the Impact of Age-Related Changes in Pediatric GI Solubility by Multivariate Data Analysis

open access: yesPharmaceutics, 2022
The aim of this study was to understand drug solubilization as a function of age and identify drugs at risk of altered drug solubility in newborns and young infants in comparison to adults.
Mariana Guimarães   +4 more
doaj   +1 more source

Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research

open access: yesPharmaceutics, 2022
Drug absorption following oral administration is determined by complex and dynamic interactions between gastrointestinal (GI) physiology, the drug, and its formulation.
Stefan Senekowitsch   +15 more
doaj   +1 more source

The biopharmaceutical anomaly [PDF]

open access: yesNature Biotechnology, 2020
Investment and funding has continued to flow into biotech, unlike most business sectors. But with healthcare and hospital budgets increasingly under pressure, do belt-tightening and consolidation lie ahead? Melanie Senior investigates, with additional reporting by Riku Lahteenmaki.
openaire   +2 more sources

Biopharmaceuticals in China

open access: yesBiotechnology Journal, 2006
AbstractThe biopharmaceutical industry, whose products are produced mainly by recombinant DNA technology, antibody technologies and cytotechnology, is the most important sector in industrial biotechnology, and is one of the most rapidly growing high‐tech industries.
Xianwen, Hu, Qingjun, Ma, Shuyong, Zhang
openaire   +3 more sources

Plasmid Biopharmaceuticals

open access: yesMicrobiology Spectrum, 2014
ABSTRACTPlasmids are currently an indispensable molecular tool in life science research and a central asset for the modern biotechnology industry, supporting its mission to produce pharmaceutical proteins, antibodies, vaccines, industrial enzymes, and molecular diagnostics, to name a few key products.
Duarte Miguel F, Prazeres   +1 more
openaire   +2 more sources

Microneedle-Mediated Transdermal Delivery of Genetic Materials, Stem Cells, and Secretome: An Update and Progression

open access: yesPharmaceutics, 2023
Medical practitioners commonly use oral and parenteral dosage forms to administer drugs to patients. However, these forms have certain drawbacks, particularly concerning patients’ comfort and compliance.
Avelia Devina Calista Nainggolan   +5 more
doaj   +1 more source

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