Results 11 to 20 of about 15,283 (290)
, 2023 Biopharmaceutics, in connection with pharmacokinetics, is the field that investigates and describes everything that happens with a medicinal product and the active substance between the moment of administration, the moment it exerts its action and the moment it is eliminated from the body. Biopharmaceutics connects the physico-chemical properties of an
Frijlink, Henderik +3 more
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British Journal of Pharmacy, 2022 Physiologically based pharmacokinetic (PBPK) modelling is a powerful alternative for paediatric clinical trials. Paediatric PBPK models require data on intestinal drug metabolising enzymes and transporter (DMET)-protein abundances, however only limited ...
Jan Goelen +2 more
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Pharmaceutics, 2022 Saponins are an important class of surface-active substances. When formulated as an active ingredient or co-used with other drugs, the effect of their surface activity on efficacy or safety must be considered.
Xingxing Dai +11 more
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Advanced and Innovative Nano-Systems for Anticancer Targeted Drug Delivery
Pharmaceutics, 2021 The encapsulation of therapeutic agents into nano-based drug delivery system for cancer treatment has received considerable attention in recent years. Advancements in nanotechnology provide an opportunity for efficient delivery of anticancer drugs.
Lu Tang +5 more
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The biopharmaceutical anomaly [PDF]
Nature Biotechnology, 2020 Investment and funding has continued to flow into biotech, unlike most business sectors. But with healthcare and hospital budgets increasingly under pressure, do belt-tightening and consolidation lie ahead? Melanie Senior investigates, with additional reporting by Riku Lahteenmaki.
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Frontiers in Endocrinology, 2022 Reducing injection-site pain (ISP) in patients with chronic conditions such as growth hormone deficiency is a valuable strategy to improve patient compliance and therapeutic efficiency.
Bita Taghizadeh +4 more
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Pharmaceutics, 2022 The aim of this study was to understand drug solubilization as a function of age and identify drugs at risk of altered drug solubility in newborns and young infants in comparison to adults.
Mariana Guimarães +4 more
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A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP [PDF]
, 2020 The application of in silico modeling to predict the in vivo outcome of an oral drug product is gaining a lot of interest. Fully relying on these models as a surrogate tool requires continuous optimization and validation.
Dickens, Joseph +15 more
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Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
Pharmaceutics, 2022 Drug absorption following oral administration is determined by complex and dynamic interactions between gastrointestinal (GI) physiology, the drug, and its formulation.
Stefan Senekowitsch +15 more
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Biotechnology Journal, 2006 AbstractThe biopharmaceutical industry, whose products are produced mainly by recombinant DNA technology, antibody technologies and cytotechnology, is the most important sector in industrial biotechnology, and is one of the most rapidly growing high‐tech industries.
Xianwen, Hu, Qingjun, Ma, Shuyong, Zhang
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