Results 41 to 50 of about 10,064 (258)

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Stem cell research in Indonesia from 2003 to 2022: A bibliometrics analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Stem cell research has become popular in Indonesia for more than a decade. The scope of research involves in vitro to animal studies as well as human trials. However, no evidence proved its trend.
Imam Rosadi, Karina Karina, Pitra Ariesta Sinta Dewi, Anggraini Barlian, Thania Fathimah Az Zahra, Viol Dhea Kharisma, Arif Nur Muhammad Ansori   +6 more
doaj   +1 more source

Environmental Insights and Sustainability Opportunities for Scaled‐Up MXene Production Without Etching

Advanced Science, EarlyView.
Through a systematic and comprehensive analysis of the environmental impacts for the emerging MXene synthesis pathways, this study presents process transformation and optimization opportunities for low‐carbon MXene production from laboratory to industrial scales.
Yushuai Huang, Peng Peng, Maoqiao Xiang, Fen Yue, Jiangyan Wang, Wenwei Liu, Qingshan Zhu   +6 more
wiley   +1 more source

Structural and In Vitro Functional Comparability Analysis of Altebrel™, a Proposed Etanercept Biosimilar: Focus on Primary Sequence and Glycosylation

Pharmaceuticals, 2019
The demand for reliable comparability studies of biosimilars grows with their increased market share. These studies focus on physicochemical, structural, functional and clinical properties to ensure that a biosimilar has no significant differences to the
Ramin Fazel, Yudong Guan, Behrouz Vaziri, Christoph Krisp, Laura Heikaus, Amirhossein Saadati, Siti Nurul Hidayah, Manasi Gaikwad, Hartmut Schlüter   +8 more
doaj   +1 more source

Palladacarboxamide Capping Reagents for Carbon Isotope Labeling and Pharmaceutical Diversification

Angewandte Chemie, EarlyView.
Herein, we present a method for carbon isotope labeling of arylamides via the coupling of air‐stable palladium carboxamide complexes and boronic ester/acids. A wide variety of functionalized boronic esters and acids have been coupled with simple palladium carboxamides complexes.
Daniel V. Hoffmann, Anika Schick, Lasse Kjær, Vitus J. Enemærke, Clemens Kaussler, Jens Torp, Pablo Martínez‐Pardo, Charles S. Elmore, Troels Skrydstrup   +8 more
wiley   +2 more sources

Precision Lignocellulosic Biorefinery: Process Regulation From Corn Stover to Products

Advanced Science, EarlyView.
This study presents a precision biorefinery framework that transforms corn stover into high‐value bioproducts through whole‐process regulation. Mechanical fractionation separates feedstock into parenchyma‐rich short fibers and vascular‐bundle‐dominant long fibers.
Xue‐Cheng Lin, Lan Wang, Tai‐Ran Pang, Ming‐Yuan Yin, Hong‐Zhang Chen   +4 more
wiley   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal‐Chelate‐Modified Deoxyribonucleoside Triphosphates

Angewandte Chemie, EarlyView.
This work presents the first enzymatic polymerization of defined metal‐chelator‐modified nucleotides that leverage polymerase fidelity for uniform (radio)metal loading with successful incorporation of five different metals: Ga, In, Tb, Lu, and Y.
Antonio A. W. L. Wong, François Bénard, David M. Perrin   +2 more
wiley   +2 more sources

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Toward Long‐Term Reliable Human‐Machine Interaction: A Flexible, Breathable, and Self‐Powered Pressure Sensor System With Firefighting Validation

Advanced Science, EarlyView.
This work develops a breathable potentiometric self‐powered pressure sensor with good wearability, using a non‐woven fabric substrate and hydrogel electrolyte. The sensor is integrated into a five‐channel smart glove to acquire reliable hand motion signals, which are processed by a CNN for identity verification and smart vehicle control in human ...
Qilong Zhang, Zhao Yao, Jiaxu Liu, Yuxuan Hou, Zhongtao Zhang, Jingwei Xue, Leonid Chernogor, Nam Young Kim, Eun Seong Kim, Yuanyue Li, Yang Li   +10 more
wiley   +1 more source