Results 51 to 60 of about 474,826 (228)

Biophysical Submesoscale Processes in the Wake of Hurricane Ivan: Simulations and Satellite Observations

open access: yesJournal of Marine Science and Engineering, 2019
Tropical cyclone induced phytoplankton productivity is examined using a tropical cyclone version of the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS®).
Travis A. Smith   +3 more
doaj   +1 more source

pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

open access: yesMolecules, 2014
Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from ...
Melanie Köhler   +6 more
doaj   +1 more source

Biophysical Mechanisms of Vaginal Smooth Muscle Contraction: The Role of the Membrane Potential and Ion Channels

open access: yesPathophysiology
The vagina is an essential component of the female reproductive system and is responsible for providing female sexual satisfaction. Vaginal smooth muscle contraction plays a crucial role in various physiological processes, including sexual arousal ...
Chitaranjan Mahapatra, Ravinder Kumar
doaj   +1 more source

Neural tube patterning: From a minimal model for rostrocaudal patterning toward an integrated 3D model

open access: yesiScience, 2021
Summary: Rostrocaudal patterning of the neural tube is a defining event in vertebrate brain development. This process is driven by morphogen gradients which specify the fate of neural progenitor cells, leading to the partitioning of the tube.
Max Brambach   +6 more
doaj   +1 more source

Protocol for adeno-associated virus-mediated optogenetic activation of olfactory output neurons in neonatal mice

open access: yesSTAR Protocols
Summary: Optogenetic manipulation has proven a powerful tool for investigating the mechanisms underlying the function of neuronal networks, but implementing the technique on mammals during early development remains challenging.
Yu-Nan Chen   +3 more
doaj   +1 more source

Chirality in Optical Trapping and Optical Binding

open access: yesPhotonics, 2015
Optical trapping is a well-established technique that is increasingly used on biological substances and nanostructures. Chirality, the property of objects that differ from their mirror image, is also of significance in such fields, and a subject of much ...
David S. Bradshaw   +3 more
doaj   +1 more source

The dawn of mathematical biology [PDF]

open access: yes, 2015
In this paper I describe the early development of the so-called mathematical biophysics, as conceived by Nicolas Rashevsky back in the 1920's, as well as his latter idealization of a "relational biology". I also underline that the creation of the journal
Hoffmann, Daniel Sander
core   +2 more sources

Advanced Therapeutics, Vaccinations, and Precision Medicine in the Treatment and Management of Chronic Hepatitis B Viral Infections; Where Are We and Where Are We Going?

open access: yesViruses, 2020
The management of chronic hepatitis B virus (CHB) infection is an area of massive unmet clinical need worldwide. In spite of the development of powerful nucleoside/nucleotide analogue (NUC) drugs, and the widespread use of immune stimulators such as ...
Ganesh Selvaraj Duraisamy   +6 more
doaj   +1 more source

Communications Biophysics [PDF]

open access: yes, 1986
Contains reports on seven research projects split into three sections, with research objective for the final section.National Institutes of Health (Grant 2 PO1 NS 13126)National Institutes of Health (Grant 5 RO1 NS 18682)National Institutes of Health ...
Braida, Louis D.   +43 more
core  

Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions

open access: yesCells, 2020
The major defense system against microbial pathogens in vertebrates is the adaptive immune response and represents an effective mechanism in cancer surveillance. T cells represent an essential component of this complex system.
Josephine Alba   +4 more
doaj   +1 more source

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