Results 71 to 80 of about 39,009 (272)

Comparative Analysis of Bioreactor Design and Scale‐Up for Cultivated Meat Using Monte Carlo‐Based Timescale Modeling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat offers a sustainable alternative to conventional livestock production but faces significant scale‐up challenges, particularly in bioreactor design for mammalian cell suspension cultures. This study presents a comparative analysis of stirred tank reactors (STR), bubble columns (BC), and airlift reactors (ALR) to assess their ...
Pieter Jan Theodoor Brorens, Marcel Ottens, Cees Haringa   +2 more
wiley   +1 more source

Build Your Bioprocess on a Solid Strain—β-Carotene Production in Recombinant Saccharomyces cerevisiae

Frontiers in Bioengineering and Biotechnology, 2019
Robust fermentation performance of microbial cell factories is critical for successful scaling of a biotechnological process. From shake flask cultivations to industrial-scale bioreactors, consistent strain behavior is fundamental to achieve the ...
Javiera López, Javiera López, Vicente F. Cataldo, Manuel Peña, Pedro A. Saa, Francisco Saitua, Maximiliano Ibaceta, Eduardo Agosin, Eduardo Agosin   +8 more
doaj   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Enzyme technology and bioprocess engineering.

, 2002
The impact of directed evolution and site-specific mutagenesis on the industrial utility of enzymatic catalysis through the modification of enzyme structure and function is clearly an important area of research in bioprocess engineering.
Panke S, Wubbolts MG
core   +1 more source

Pectinase‐Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development

Biotechnology and Bioengineering, EarlyView.
This picture demonstrates a unified strategy for sustainable pectinase production, focusing on microbial bioproduction, innovative strategies in enzyme engineering (Protein engineering, rational enzyme design, directed evolution and heterologous expression) and various applications in industry, including food, textiles, pulp and paper, agriculture and ...
Nisha Sharma, Dimple Tanwar, Usha Grewal, Murugesan Mohana Keerthi, Yogesh K. Ahlawat, Nitin Pandey, Chirag G. Makvana   +6 more
wiley   +1 more source

Equipment Qualification of the 3mm BioProcess System [PDF]

, 2013
Executive Summary Equipment Qualification of the 3mm BioProcess System Althea Technologies Inc. Joey Stark May 13, 2013 Professional Science Masters Degree Program California State University San Marcos Equipment plays an integral role in the downstream ...
Joey Stark
core   +1 more source

Quantitative Bioprocess Containment Validation [PDF]

, 2000
The safe use of genetically modified micro-organisms (GMMOs) for the industrial manufacture of therapeutic and other products depends on the design, implementation and validation of effective containment principles.
Bradley, Michael Ian
core   +1 more source

Microbial Conversion of Glycerol Into 1,3‐Propanediol by Fermentation: Review of Fundamentals and Operational Strategies

Microbial Biotechnology
Over the past decades, biodiesel production has sharply increased worldwide and has led to an overproduction of glycerol, as by‐product. Therefore, glycerol is not only produced at low cost with a wide availability but is also a versatile precursor of ...
María Fernanda Pérez‐Bernal, Roman Moscoviz, Xiaoli Wang, Nicolas Bernet, Eric Trably   +4 more
doaj   +1 more source

Extremophilic Exopolysaccharides: Bioprocess and Novel Applications in 21st Century

Fermentation
Extremophiles, microorganisms blooming in extreme environmental conditions, hold particular significance in the domain of microbial research. This review paper focuses on extremophilic microorganisms, emphasizing their adaptations and the diverse ...
Chandni Upadhyaya, Hiren Patel, Ishita Patel, Trushit Upadhyaya   +3 more
doaj   +1 more source

Bioprocess Eng.

, 1995
The hydrolysis of sunflower oil using Candida cylindracea lipase in reversed micelles of AOT/isooctane was investigated. The inhibition caused by substrate and hydrolysis products has been found in the process of reaction. It was revealed that the extent
CHEN, JY, CHANG, QL
core