Results 81 to 90 of about 39,009 (272)

Bioprocess exploitation of microaerobic auto-induction using the example of rhamnolipid biosynthesis in Pseudomonas putida KT2440

Background In biomanufacturing of surface-active agents, such as rhamnolipids, excessive foaming is a significant obstacle for the development of high-performing bioprocesses.
Grether, Jakob, Rudolf Hausmann, Willems, Leon, Schmiegelt, Tabea, Elvio Henrique Benatto Perino, Holger Dittmann, Lars Lilge, Hausmann, Rudolf, Tabea Schmiegelt, Philipp Hubel, Dittmann, Holger, Benatto Perino, Elvio Henrique, Hubel, Philipp, Lilge, Lars, Jakob Grether, Leon Willems   +15 more
core   +1 more source

Host Cell Protein Challenges in Antibody Processing: Insights Into Persistence and Mitigation Strategies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Persistence of HCPs remains a major purification challenge in biopharmaceutical manufacturing with direct consequences for product quality, patient safety, and regulatory compliance. Over the last two decades, deeper insights into the mechanisms driving HCP persistence have clarified why certain proteins evade removal during purification ...
Younghoon Oh, Andrew Cooke, Harshal Soni, Susan Liu, Mamadou Bah, Brianna Bellis, Laura Smith, Michael Capaldi, Nicholas Levy, Erik Wilhelm, Kristopher Barnthouse   +10 more
wiley   +1 more source

Erratum: Production of chitosan from Aspergillus niger and quantitative evaluation of the process using adapted analytical tools (Biotechnology and Bioprocess Engineering, (2024), 29, 5, (942-954), 10.1007/s12257-024-00124-3)

776Correction to:Biotechnology and Bioprocess Engineering (2024) 29:942-954https://doi.org/10.1007/s12257-024-00124-3 The original version of this article contained several errors which were corrected: Fig.
Dyballa, Michael Martin, Zibek, Susanne, Heuer, Saskia, Krake, Simon, Conzelmann, C., Hahn, Thomas   +5 more
core   +1 more source

Expanding Metabolic Online Monitoring Capabilities in 96‐Deepwell Microtiter Plates by Combining Optoelectronic O2 and CO2 Sensors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT To increase the information content in early stages of bioprocess development, various technologies have been introduced for monitoring cultivations in microtiter plates (MTPs). Besides spectroscopical measurements, like in the BioLector technology, optical measurements with luminescent sensors, placed directly in the cultivation medium ...
Robert Dinger, David Pfeifer, David Flitsch, Jan P. Fischer, Clemens Lattermann, Sergey M. Borisov, Jochen Büchs   +6 more
wiley   +1 more source

Toward an innovation radar for cultivated meat: exploring process technologies for cultivated meat and claims about their social impacts

Frontiers in Sustainable Food Systems
IntroductionCultivated meat has received growing attention since claims were made that cultivated meat can be produced more ethically and sustainably than the current meat production.
Lisa Woelken, Dagmara M. Weckowska, Carsten Dreher, Cornelia Rauh   +3 more
doaj   +1 more source

Bioprocess Eng.

, 1999
The effect of fungal elicitor, derived from mycelial extracts of Penicillium chysogenum 3446, on artemisinin production in hairy root cultures of Artemisia annua L was studied.
Ouyang, F., Li, G., Ye, H., Xu, X., Wang, Y., Liu, C.   +5 more
core  

Model‐Driven Monitoring and Parameter‐Based Development of an Escherichia coli Fed‐Batch Process for Production of a Fab Antibody Fragment Across Scales

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Maintaining consistent cellular physiology during bioprocess scale‐up or scale‐down is key to developing robust processes. However, the reliability of scale‐down bioreactor systems remains debated. Although the calibration of physiological parameters in mechanistic models across scales has been proposed as a scale‐down strategy, few studies ...
Fabian Schröder‐Kleeberg, Lucas Kaspersetz, Markus Zoellkau, Markus Glaser, Markus Brunner, Christian Bosch, Annina Kemmer, M. Nicolas Cruz Bournazou, Peter Neubauer   +8 more
wiley   +1 more source

Automated Data‐Efficient Symbolic Regression for Interpretable Bioprocess Model Development

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioprocessing is central to the sustainable manufacture of pharmaceuticals, food products, and renewable chemicals. Consequently, developing high‐fidelity kinetic models to facilitate accurate process prediction, optimisation, and scale‐up is a top research priority.
Luca Riezzo, Alexander Rogers, Harry Kay, Dongda Zhang   +3 more
wiley   +1 more source

Bioprocessing Data for the Production of Marine Enzymes

Marine Drugs, 2010
This review is a synopsis of different bioprocess engineering approaches adopted for the production of marine enzymes. Three major modes of operation: batch, fed-batch and continuous have been used for production of enzymes (such as protease, chitinase ...
Sreyashi Sarkar, Arnab Pramanik, Anindita Mitra, Joydeep Mukherjee   +3 more
doaj   +1 more source

Bioprocess Eng.

, 2000
The effect of air flow rate upon scleroglucan production in batch cultures of S. glucanicum NRRL 3006 cultivated in airlift reactor with internal loop was studied using air flow rates from 0.25 m(3)/h to 1.00 m(3)/h.
Kang, X, Wang, Y, Harvey, LM, McNeil, B
core