Results 41 to 50 of about 2,229,837 (349)

Inflammation in benign prostate tissue and prostate cancer in the finasteride arm of the Prostate Cancer Prevention Trial [PDF]

, 2016
BACKGROUND: A previous analysis of the placebo arm of the Prostate Cancer Prevention Trial (PCPT) reported 82% overall prevalence of intraprostatic inflammation and identified a link between inflammation and higher-grade prostate cancer and serum PSA ...
Barber, John R, De Marzo, Angelo M, Drake, Charles G, Goodman, Phyllis J, Gurel, Bora, Kristal, Alan R, Lippman, Scott M, Lucia, M. Scott, Murtola, Teemu J, Nelson, William G, Parnes, Howard L, Peskoe, Sarah B, Platz, Elizabeth A, Sutcliffe, Siobhan, Thompson, Ian M, Jr., Umbehr, Martin   +15 more
core   +2 more sources

Immunohistochemical expression of BerEP4, CK7 and EMA in basal cell carcinoma of the skin

Bangabandhu Sheikh Mujib Medical University Journal, 2019
The aim of this study was to evaluate the immunohistochemical expression status of BerEP4, EMA and CK7 in cutaneous basal cell carcinoma (BCC) and to find out whether there is some difference in the expression pattern related to the anatomic location of ...
Vladimír Bartoš
doaj   +1 more source

Diminishing Use of Liver Biopsy among Liver Transplant Recipients for Hepatitis C. [PDF]

, 2017
Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality.
Aby, Elizabeth, Agopian, Vatche, Busuttil, Ronald W, French, Samuel W, Grotts, Jonathan F, Jimenez, Melissa A, Saab, Sammy   +6 more
core   +1 more source

Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]

, 2020
Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.), Brosens, Jan J., Da Costa, Maria José Minhoto Diniz, Ewington, Lauren J., Fishwick, Katherine, Fujihara, Risa, Kimani, Peter K., Lacey, Lauren, Lucas, Emma S., Muter, Joanne, Polanco, Angela, Quenby, Siobhan, Takeda, Satoru, Tewary, Shreeya   +13 more
core   +1 more source

Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Cell Death and Disease, 2021
TEFM (transcription elongation factor of mitochondria) has been identified as a novel nuclear-encoded transcription elongation factor in the transcription of mitochondrial genome.
Lixin Wan, Yang Wang, Zijie Zhang, Jiaxin Wang, Menglan Niu, Yuanyuan Wu, Yating Yang, Yongxia Dang, Shuang Hui, Meng Ni, Bo Wan, Dengke Bao   +11 more
doaj   +1 more source

Circular RNAs Are Promising Biomarkers in Liquid Biopsy for the Diagnosis of Non-small Cell Lung Cancer

Frontiers in Molecular Biosciences, 2021
The high incidence and mortality of lung cancer make early detection of lung cancer particularly important. At present, the diagnosis of lung cancer mainly depends on diagnostic imaging and tissue biopsy. However, current diagnostics are not satisfactory
Lanxiang Huang, Lanxiang Huang, Yuan Rong, Yuan Rong, Xuan Tang, Xuan Tang, Kezhen Yi, Kezhen Yi, Jianyuan Wu, Fubing Wang, Fubing Wang, Fubing Wang   +11 more
doaj   +1 more source

Prostate MRI, with or without MRI-targeted biopsy, and systematic biopsy for detecting prostate cancer.

Cochrane Database of Systematic Reviews, 2019
BACKGROUND Multiparametric magnetic resonance imaging (MRI), with or without MRI-targeted biopsy, is an alternative test to systematic transrectal ultrasonography-guided biopsy in men suspected of having prostate cancer.
Frank-Jan H. Drost, D. Osses, D. Nieboer, E. Steyerberg, C. Bangma, M. Roobol, I. Schoots   +6 more
semanticscholar   +1 more source

NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment

Molecular Oncology, 2021
Despite impressive and durable responses, nonsmall cell lung cancer (NSCLC) patients treated with anaplastic lymphoma kinase (ALK) inhibitors (ALK‐Is) ultimately progress due to development of resistance.
Estela Sánchez‐Herrero, Roberto Serna‐Blasco, Vadym Ivanchuk, Rosario García‐Campelo, Manuel Dómine Gómez, José M. Sánchez, Bartomeu Massutí, Noemi Reguart, Carlos Camps, Sandra Sanz‐Moreno, Silvia Calabuig‐Fariñas, Eloísa Jantus‐Lewintre, Magdalena Arnal, Dietmar Fernández‐Orth, Virginia Calvo, Víctor González‐Rumayor, Mariano Provencio, Atocha Romero   +17 more
doaj   +1 more source

Next-generation sequencing in liquid biopsy: cancer screening and early detection

Human Genomics, 2019
In recent years, the rapid development of next-generation sequencing (NGS) technologies has led to a significant reduction in sequencing cost with improved accuracy.
Ming Chen, Hongyu Zhao
semanticscholar   +1 more source

Teaching percutaneous renal biopsy using unfixed human cadavers [PDF]

, 2015
Background: Percutaneous renal biopsy (PRB) is an important diagnostic procedure. Despite advances in its safety profile there remains a small but significant risk of bleeding complications.
Ali, Khalid A., Geddes, Colin, Mackinnon, Bruce, Oliver, Scott W., Patel, Rajan K.   +4 more
core   +2 more sources