Results 41 to 50 of about 1,605,786 (390)

Prostate biopsy tracking with deformation estimation [PDF]

, 2011
Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low sensitivity. Also, it is difficult for the clinician to follow the sampling protocol accurately under 2D US control
arxiv   +1 more source

Using deep learning to detect patients at risk for prostate cancer despite benign biopsies [PDF]

arXiv, 2021
Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate, and tumour lesions in regions between biopsy cores can be missed, leading to a well-known low sensitivity to ...
arxiv  

Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology

Gut, 2020
Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes.
J. Neuberger, J. Patel, H. Caldwell, S. Davies, Vanessa Hebditch, C. Hollywood, S. Hubscher, S. Karkhanis, W. Lester, N. Roslund, R. West, J. Wyatt, M. Heydtmann   +12 more
semanticscholar   +1 more source

Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features [PDF]

arXiv, 2021
Goal: Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies - a time-consuming, laborious task that is difficult to standardize. One of the main challenges in automating this process, like
arxiv  

Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer.

Journal of the American Medical Association (JAMA), 2015
IMPORTANCE Targeted magnetic resonance (MR)/ultrasound fusion prostate biopsy has been shown to detect prostate cancer. The implications of targeted biopsy alone vs standard extended-sextant biopsy or the 2 modalities combined are not well understood ...
M. Siddiqui, S. Rais-Bahrami, B. Turkbey, A. George, J. Rothwax, Nabeel A. Shakir, Chinonyerem Okoro, Dima Raskolnikov, H. Parnes, W. Linehan, M. Merino, R. Simon, P. Choyke, B. Wood, P. Pinto   +14 more
semanticscholar   +1 more source

Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β‐catenin signaling

Molecular Oncology, 2020
Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC) initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be involved in HCC. In this study, we explored how lncRNA LINC00662 may influence HCC
Xiaohui Tian, Yuanyuan Wu, Yating Yang, Jiaxin Wang, Menglan Niu, Shanjun Gao, Tao Qin, Dengke Bao   +7 more
doaj   +1 more source

Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers

Nature Network Boston, 2019
During cancer therapy, tumor heterogeneity can drive the evolution of multiple tumor subclones harboring unique resistance mechanisms in an individual patient1–3. Previous case reports and small case series have suggested that liquid biopsy (specifically,
A. Parikh, I. Leshchiner, Liudmila Elagina, L. Goyal, Chaya Levovitz, G. Siravegna, D. Livitz, Kahn Rhrissorrakrai, Elizabeth E Martin, E. V. Van Seventer, M. Hanna, Kara Slowik, F. Utro, C. Pinto, Alicia Wong, B. Danysh, Ferran Fece de la Cruz, Isobel J. Fetter, Brandon Nadres, Heather A. Shahzade, Jill N. Allen, L. Blaszkowsky, J. Clark, B. Giantonio, Janet E. Murphy, R. Nipp, E. Roeland, David P. Ryan, C. Weekes, E. Kwak, J. Faris, J. Wo, F. Aguet, I. Dey‐Guha, M. Hazar-Rethinam, D. Dias-Santagata, David T. Ting, Andrew X. Zhu, Theodore S. Hong, Todd R. Golub, A. Iafrate, V. Adalsteinsson, A. Bardelli, L. Parida, D. Juric, G. Getz, R. Corcoran   +46 more
semanticscholar   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Amniotic Band Sequence in an Intrauterine Fetal Demise at 17 weeks of Pregnancy: A case report

Journal of the Dow University of Health Sciences
Amniotic band sequence is a rare disorder characterised by various congenital abnormalities due to constrictions of certain parts of the fetal body by fibrous bands derived from the amniotic sac. A 29-year-old pregnant woman with a missed abortion at 17
Vladimir Bartos
doaj   +6 more sources

Diffusion-weighted MRI-guided needle biopsies permit quantitative tumor heterogeneity assessment and cell load estimation [PDF]

arXiv, 2021
Quantitative information on tumor heterogeneity and cell load could assist in designing effective and refined personalized treatment strategies. It was recently shown by us that such information can be inferred from the diffusion parameter D derived from the diffusion-weighted MRI (DWI) if a relation between D and cell density can be established ...
arxiv