Results 51 to 60 of about 1,605,786 (390)
Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy.
Cancer Discovery, 2016 UNLABELLED "Liquid biopsy" focusing on the analysis of circulating tumor cells (CTC) and circulating cell-free tumor DNA (ctDNA) in the blood of patients with cancer has received enormous attention because of its obvious clinical implications for ...
C. Alix-Panabières, K. Pantel
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Ultrasound imaging in the general practitioner’s office – a literature review
Journal of Ultrasonography, 2016 Ultrasound, which is a safe and non-invasive diagnostic modality that uses more and more advanced imaging techniques, has become the first-choice examination in various diseases.
Alicja Genc +4 more
doaj +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Role of lung ultrasound inpaediatric patients
Pediatria i Medycyna Rodzinna, 2014 Transthoracic lung ultrasound is ultrasonographic assessment of the lungs, parietal and visceral pleura and the space between these two membranes. It is a part of chest ultrasound examination which also includes assessment of the ribs, intercostal ...
Magdalena Kryger, Wojciech Kosiak
doaj +1 more source
Bone & Joint Open, 2022 AimsHip dysplasia (HD) leads to premature osteoarthritis. Timely detection and correction of HD has been shown to improve pain, functional status, and hip longevity. Several time-consuming radiological measurements are currently used to confirm HD.
Holden Archer +10 more
doaj +1 more source
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
Scientific Reports, 2018 Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated,
Magdalena Kasendra +12 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Next-generation sequencing in liquid biopsy: cancer screening and early detection
Human Genomics, 2019 In recent years, the rapid development of next-generation sequencing (NGS) technologies has led to a significant reduction in sequencing cost with improved accuracy.
Ming Chen, Hongyu Zhao
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source