Results 161 to 170 of about 4,698 (199)

Screening for Biopterin Disorders in PKU

Pediatrics, 1980
It is now recognized (Pediatrics 65:806, 1980) that a small proportion of cases of phenylketonuria (PKU) may be due to abnormalities in the metabolism of biopterin. These cases do not respond to the restriction of dietary phenylalanine, but may be benefited by neurotransmitter replacement therapy. A specific diagnosis is therefore desirable.
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Biopterin: Reduced form in Ascaris lumbricoides

Experimental Parasitology, 1970
Abstract A blue fluorescent substance which was supposed to be “Ascaris-blue” was extracted from Ascaris muscle. After Chromatographic purification, the substance was identified as biopterin, 2-amino-4-hydroxy-6-(erythro-1′, 2′-dihydroxypropyl)pteridine.
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A new synthesis of biopterin

Journal of the Chemical Society C: Organic, 1969
An unambiguous synthesis of biopterin [2-amino-6-(L-erythro-1,2-dihydroxypropyl)pteridin-4-(3H)-one] is described; based on an improved synthesis of L-neopterin. The synthesis yields biopterin, a naturally occurring pteridine, in a pure, crystalline form without recourse to chromatography. D-Biopterin and D-neopterin are also described.
K. J. M. Andrews, W. E. Barber, B. P. Tong   +2 more
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Hyperphenylalaninaemia caused by defects in biopterin metabolism

Journal of Inherited Metabolic Disease, 1985
AbstractThe hepatic phenylalanine hydroxylating system consists of three essential components, phenylalanine hydroxylase, dihydropteridine reductase and the non‐protein coenzyme, tetrahydrobiopterin. The reductase and the pterin coenzyme are also essential components of the tyrosine and tryptophan hydroxylating systems.
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New aspects in biopterin biosyntheses

1981
A human kidney preparation which catalyzes the conversion of D-erythro-dihydroneopterin triphosphate (NeH2P3) to dihydrobiopterin (BH2), sepiapterin, pyruvate and pterin in the presence of Mg++ and NADPH was studied. After incubation with NeH2P3, the formation of Tanaka’s compound X (probably 6-(1’,2’-dioxopropyl)-7,8-dihydropterin) could be proven as ...
H-Ch Curtius, M Häusermann, A Niederwieser, W Endres, M Viscontini   +4 more
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13C-phenylalanine breath test and serum biopterin in schizophrenia, bipolar disorder and major depressive disorder.

Journal of Psychiatric Research, 2018
T. Teraishi, M. Kajiwara, H. Hori, D. Sasayama, S. Hidese, J. Matsuo, Ikki Ishida, Yasuhiro Kajiwara, Y. Ozeki, M. Ota, K. Hattori, T. Higuchi, H. Kunugi   +12 more
semanticscholar   +1 more source

BIOPTERIN AND ORGAN TRANSPLANTATION

The Lancet, 1988
J L, Dhondt, M P, Walter, F, Bauters, J P, Jouet   +3 more
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Microcystbiopterins A-E, five O-methylated biopterin glycosides from two Microcystis spp. bloom biomasses.

Phytochemistry, 2016
M. Lifshits, Dimitri Kovalerchik, S. Carmeli   +2 more
semanticscholar   +1 more source

Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system.

Biochemical and Biophysical Research Communications - BBRC, 2015
I. Kawahata, S. Ohtaku, Y. Tomioka, H. Ichinose, T. Yamakuni   +4 more
semanticscholar   +1 more source

Disturbed biopterin and folate metabolism in the Qdpr‐deficient mouse

FEBS Letters, 2014
Feng Xu, Y. Sudo, Sho Sanechika, J. Yamashita, Shozaburo Shimaguchi, Shunnosuke Honda, C. Sumi-Ichinose, Masayo Mori-Kojima, R. Nakata, T. Furuta, M. Sakurai, M. Sugimoto, T. Soga, Kazunao Kondo, H. Ichinose   +14 more
semanticscholar   +1 more source