Results 221 to 230 of about 8,158 (274)
Structure-based design, and development of amidinyl, amidoximyl and hydroxamic acid based organic molecules as novel antimalarial drug candidates. [PDF]
Adebayo GP +6 more
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Synthesis of biopterin and related pterin glycosides
AbstractCertain pterins having a hydroxyalkyl side chain at C‐6 have been found as glycosidic forms in certain prokaryotes, such as 2′‐O‐(α‐D‐glucopyranosyl)biopterin from various kinds of cyanobacteria, and limipterin from a green sulfur photosynthetic bacterium.
Tadashi, Hanaya, Hiroshi, Yamamoto
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Psychiatric Manifestations in Patients with Biopterin Defects.
Neuropediatrics, 2022Psychiatric manifestations in patients with tetrahydrobiopterin (BH4) defects are common, and may occur even with treatment of the underlying disorder.
M. Parfyonov +4 more
semanticscholar +1 more source
Liebigs Annalen der Chemie, 1989
AbstractThe synthesis of (‐)‐biopterin (1) was accomplished by employing (1S,2S)‐1‐(2‐furyl)‐2‐(trityloxy)‐1‐propanol (6), derived from ethyl (S)‐lactate, as building block for the side chain.
Kenji Mori, Haruhiko Kikuchi
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AbstractThe synthesis of (‐)‐biopterin (1) was accomplished by employing (1S,2S)‐1‐(2‐furyl)‐2‐(trityloxy)‐1‐propanol (6), derived from ethyl (S)‐lactate, as building block for the side chain.
Kenji Mori, Haruhiko Kikuchi
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Journal of Mass Spectrometry, 2019
Urinary biopterin (Bio) and neopterin (Neo) are important markers for clinical diagnosis of hyperphenylalaninemia. Herein, we developed a high-throughput analysis method based on electrospray ionization mass spectrometry (ESI-MS) with polymer tips for ...
X. Yang +7 more
semanticscholar +1 more source
Urinary biopterin (Bio) and neopterin (Neo) are important markers for clinical diagnosis of hyperphenylalaninemia. Herein, we developed a high-throughput analysis method based on electrospray ionization mass spectrometry (ESI-MS) with polymer tips for ...
X. Yang +7 more
semanticscholar +1 more source
Neurochemical Research, 1976
Intraperitoneally injected [(14)C]biopterin (B), dihydrobiopterin (BH2), and tetrahydrobiopterin (BH4) penetrated the brain rapidly, but in amounts sufficient to represent only a minor source of supply. Unlike isobiopterin, B was rapidly reduced to BH2 in brain.
E M, Gal, G, Hanson, A, Sherman
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Intraperitoneally injected [(14)C]biopterin (B), dihydrobiopterin (BH2), and tetrahydrobiopterin (BH4) penetrated the brain rapidly, but in amounts sufficient to represent only a minor source of supply. Unlike isobiopterin, B was rapidly reduced to BH2 in brain.
E M, Gal, G, Hanson, A, Sherman
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Chlorination of Biopterin in Water: Deciphering the Kinetics, Disinfection Byproducts, and Toxicity.
Environmental Science and TechnologyPterins, including biopterin prevalent during cyanobacterial blooms, are nitrogen-containing heterocyclic compounds ubiquitous in both natural and engineered environments.
Yanting Zuo +7 more
semanticscholar +1 more source
Pteridine, LXXV. Synthese und Eigenschaften von Biopterin und Biopterin‐Analogen
Liebigs Annalen der Chemie, 1984AbstractDie Synthese von Biopterin (6), seinem 2‐N,N‐Dimethyl‐ (8) und 4‐ Thioxo‐Derivat (19) sowie von Biolumazin (7) wird beschrieben. Durch Umsetzung von Biopterin mit α‐Acetoxyisobuttersäurechlorid läß sich die Seitenkette zu 6‐(L‐threo‐2‐Acetoxy‐1‐chlorpropyl)pterin (10) modifizieren, das als Ausgangsmaterial fär weitere Derivatisierungen dienen ...
Mathias Kappel +2 more
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Pteridine diuretics as biopterin antagonists
Biochemical Pharmacology, 1974Abstract A series of pteridines having varying degrees of diuretic activity were tested for their effects on the growth of the pteridine-requiring flagellate, Crithidia fasciculata . Inhibition of growth was correlated with diuretic activity insofar as compounds devoid of diuretic effects were uninhibitory and active inhibitors were also good to ...
V C, Dewey, G W, Kidder
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