Results 231 to 240 of about 8,158 (274)
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Physiological and clinical chemistry of biopterin
Medicinal Research Reviews, 1989Chimie, dosage de la biopterine. Biosynthese de la tetrahydrobiopterine. Role physiologique de la tetrahydrobiopterine comme cofacteur des monooxygenases necessitant la pterine.
T, Nagatsu, S, Matsuura, T, Sugimoto
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Biosynthesis of Biopterin by Rat Brain
Journal of Neurochemistry, 1982Abstract: A method for the determination of [14C]biopterin biosynthesis from [14C]guanosine‐5′‐triphosphate by a desalted preparation from rat striatum, based on sequential reverse‐phase and cation‐exchange high performance liquid chromatography, is described.
G, Kapatos, S, Katoh, S, Kaufman
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Plasma biopterin levels and tetrahydrobiopterin responsiveness
Molecular Genetics and Metabolism, 2005Tetrahydrobiopterin (BH4) responsive hyperphenylalaninemia (HPA) with a mutant phenylalanine hydroxylase (PAH) gene was found during neonatal screening for PKU. This study determined blood BH4 and phenylalanine in two patients with hyperphenylalaninemia following oral load with BH4 10 mg/kg. Our patients underwent neonatal screening for PKU, had normal
Haruo, Shintaku +4 more
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Biopterin and neopterin in human saliva
Life Sciences, 1989Presence of biopterin and neopterin in human saliva was investigated by HPLC after iodine oxidation in acidic medium. Concentrations of biopterin and neopterin (M +/- SEM) were 1.271 +/- 0.254 and 0.358 +/- 0.075 ng per ml, respectively, in saliva of apparently healthy young male adults, ages 20 to 22 years (n = 9).
S, Katoh +3 more
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Biopterin cofactor and monoamine-synthesizing monooxygenases
Neurochemistry International, 1983The activities of three pterin-requiring monooxygenases, phenylalanine hydroxylase, tyrosine hydroxylase and tryptophan hydroxylase, are regulated by the level of the pterin cofactor, (6R)- l -erythro- tetrahydrobiopterin , which is synthesized from guanosine triphosphate (GTP).
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ChemInform Abstract: PTERIDINES, LXXV. SYNTHESIS AND PROPERTIES OF BIOPTERIN AND BIOPTERIN ANALOGS
Chemischer Informationsdienst, 1985AbstractAus dem Desoxy‐arabinose‐hydrazon (II) und den Diaminen ( l) werden Biopterin ( 111a), dessen Dimethyl‐Derivat (IIIc) und Biolumazin (IIIb) hergestellt.
M. KAPPEL, R. MENGEL, W. PFLEIDERER
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Neurochemical Research, 1981
Repeated intraventricular injections of 2,4-diamino-6-hydroxypyrimidine (DAO-Pyr), inhibitor of D-erythro-q-dihydroneopterin triphosphate synthetase, inhibited q-BH2 synthesis from GTP, markedly increased accumulation of 2-amino-4-hydroxy-5 (or -6)-formamido-6-triphosphoribosylaminopyrimidine (FPyd-P3) and brought about a 60% decrease in the in vivo of
E M, Gál, D H, Whitacre
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Repeated intraventricular injections of 2,4-diamino-6-hydroxypyrimidine (DAO-Pyr), inhibitor of D-erythro-q-dihydroneopterin triphosphate synthetase, inhibited q-BH2 synthesis from GTP, markedly increased accumulation of 2-amino-4-hydroxy-5 (or -6)-formamido-6-triphosphoribosylaminopyrimidine (FPyd-P3) and brought about a 60% decrease in the in vivo of
E M, Gál, D H, Whitacre
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Urinary neopterin and biopterin indicate that inflammation has a role in autism spectrum disorder
Metabolic brain disease, 2023Ece Oge-Enver +7 more
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Screening for Biopterin Disorders in PKU
Pediatrics, 1980It is now recognized (Pediatrics 65:806, 1980) that a small proportion of cases of phenylketonuria (PKU) may be due to abnormalities in the metabolism of biopterin. These cases do not respond to the restriction of dietary phenylalanine, but may be benefited by neurotransmitter replacement therapy. A specific diagnosis is therefore desirable.
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Progress in Neuro-psychopharmacology and Biological Psychiatry, 2022
D. Cavaleri +11 more
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D. Cavaleri +11 more
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