First Synthesis of a Representative, Natural Pterin Glycoside: 2’-O-(α-D-Glucopyranosyl)biopterin [PDF]
, 2009 Glycosylation of N(2)-(N,N-dimethylaminomethylene)-1’-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl) ethyl]biopterin (14) with the novel donor 4,6-di-O-acetyl-2,3-di-O-(4-methoxybenzyl)-α-D-glucopyranosyl bromide (19) in the presence of silver triflate and ...
Hanaya, Tadashi +2 more
core
A unique dual activity amino acid hydroxylase in Toxoplasma gondii [PDF]
, 2009 The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes encoding tyrosine hydroxylase; that produces L-DOPA. The encoded enzymes metabolize phenylalanine as well as tyrosine with substrate preference for tyrosine.
Gaskell, EA +4 more
core +1 more source
Inflammation and oxidative stress caused by nitric oxide synthase uncoupling might lead to left ventricular diastolic and systolic dysfunction in patients with hypertension [PDF]
, 2018 K
Bodó, Imre +13 more
core +1 more source
Quantification of Neurotransmitters in Mouse Brain Tissue by Using Liquid Chromatography Coupled Electrospray Tandem Mass Spectrometry [PDF]
, 2014 A simple and rapid liquid chromatography tandem mass spectrometry method has been developed for the determination of BH4, DA, 5-HT, NE, EP, Glu, and GABA in mouse brain using epsilon-acetamidocaproic acid and isotopically labeled neurotransmitters as ...
Hak Rim Kim +3 more
core +1 more source
Inflammation and oxidative stress caused by nitric oxide synthase uncoupling might lead to left ventricular diastolic and systolic dysfunction in patients with hypertension [PDF]
, 2015 Objective: To investigate the role of oxidative stress, inflammation, hypercoagulability and neuroendocrine activation in the transition of hypertensive heart disease to heart failure with preserved ejection fraction (HFPEF).
Bodó I +14 more
core +2 more sources
Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression [PDF]
, 2018 GTP cyclohydrolase I (GTPCH) catalyses the first and rate-limiting reaction in the synthesis of tetrahydrobiopterin (BH4), an essential cofactor for nitric oxide synthases (NOS).
Al Haj Zen, Ayman +9 more
core +2 more sources
Is tetrahydrobiopterin a therapeutic option in diabetic hypertensive patients? [PDF]
, 2010 Nitric oxide (NO) is an important regulator of vascular tone, and is also an antithrombotic, anti-inflammatory, antiproliferative, and antiatherogenic factor.
Escalante-Acosta, Bruno Alfonso +3 more
core +3 more sources
Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth. [PDF]
Hypertension, 2021 Chuaiphichai S +16 more
europepmc +1 more source
Associations of Biopterins and ADMA with Vascular Function in Peripheral Microcirculation from Patients with Chronic Kidney Disease. [PDF]
Int J Mol Sci, 2023 Arefin S +4 more
europepmc +1 more source
Radioimmunoassay for biopterin.
Proceedings of the Japan Academy, Series B, 1979 Nobuhiko Nakazawa +9 more
openaire +3 more sources