Results 81 to 90 of about 873 (118)

Serum Neopterin, Biopterin, Tryptophan, and Kynurenine Levels in Patients with Fabry Disease [PDF]

Balkan Med J
Uçar T, Cansever MŞ, Isat E, Zubarioğlu T, Aktuğlu Zeybek AÇ, Topçu B, Seyahi N, Kıykım E.   +7 more
europepmc   +1 more source

In Silico Structural Insights and Potential Inhibitor Identification Based on the Benzothiazole Core for Targeting Leishmania major Pteridine Reductase 1. [PDF]

ACS Omega
de O Viana J, Weber KC, da Cruz LEG, Santos RO, Rocha GB, Jordão AK, Barbosa EG.   +6 more
europepmc   +1 more source

Genotype-Phenotype Correlation in a Large Cohort of Eastern Sicilian Patients Affected by Phenylketonuria: Newborn Screening Program, Clinical Features, and Follow-Up. [PDF]

Nutrients
Consentino MC, La Spina L, Meli C, Messina M, Lo Bianco M, Sapuppo A, Pappalardo MG, Iacobacci R, Arena A, Vecchio M, Ruggieri M, Polizzi A, Praticò AD.   +12 more
europepmc   +1 more source

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Synthesis of (‐)‐Biopterin

Liebigs Annalen der Chemie, 1989
AbstractThe synthesis of (‐)‐biopterin (1) was accomplished by employing (1S,2S)‐1‐(2‐furyl)‐2‐(trityloxy)‐1‐propanol (6), derived from ethyl (S)‐lactate, as building block for the side chain.
Kenji Mori, Haruhiko Kikuchi
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Biopterin

Neurochemical Research, 1976
Intraperitoneally injected [(14)C]biopterin (B), dihydrobiopterin (BH2), and tetrahydrobiopterin (BH4) penetrated the brain rapidly, but in amounts sufficient to represent only a minor source of supply. Unlike isobiopterin, B was rapidly reduced to BH2 in brain.
E M, Gal, G, Hanson, A, Sherman
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Pteridine, LXXV. Synthese und Eigenschaften von Biopterin und Biopterin‐Analogen

Liebigs Annalen der Chemie, 1984
AbstractDie Synthese von Biopterin (6), seinem 2‐N,N‐Dimethyl‐ (8) und 4‐ Thioxo‐Derivat (19) sowie von Biolumazin (7) wird beschrieben. Durch Umsetzung von Biopterin mit α‐Acetoxyisobuttersäurechlorid läß sich die Seitenkette zu 6‐(L‐threo‐2‐Acetoxy‐1‐chlorpropyl)pterin (10) modifizieren, das als Ausgangsmaterial fär weitere Derivatisierungen dienen ...
Mathias Kappel, Rolf Mengel, Wolfgang Pfleiderer   +2 more
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Pteridine diuretics as biopterin antagonists

Biochemical Pharmacology, 1974
Abstract A series of pteridines having varying degrees of diuretic activity were tested for their effects on the growth of the pteridine-requiring flagellate, Crithidia fasciculata . Inhibition of growth was correlated with diuretic activity insofar as compounds devoid of diuretic effects were uninhibitory and active inhibitors were also good to ...
V C, Dewey, G W, Kidder
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Physiological and clinical chemistry of biopterin

Medicinal Research Reviews, 1989
Chimie, dosage de la biopterine. Biosynthese de la tetrahydrobiopterine. Role physiologique de la tetrahydrobiopterine comme cofacteur des monooxygenases necessitant la pterine.
T, Nagatsu, S, Matsuura, T, Sugimoto
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Biosynthesis of Biopterin by Rat Brain

Journal of Neurochemistry, 1982
Abstract: A method for the determination of [14C]biopterin biosynthesis from [14C]guanosine‐5′‐triphosphate by a desalted preparation from rat striatum, based on sequential reverse‐phase and cation‐exchange high performance liquid chromatography, is described.
G, Kapatos, S, Katoh, S, Kaufman
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Plasma biopterin levels and tetrahydrobiopterin responsiveness

Molecular Genetics and Metabolism, 2005
Tetrahydrobiopterin (BH4) responsive hyperphenylalaninemia (HPA) with a mutant phenylalanine hydroxylase (PAH) gene was found during neonatal screening for PKU. This study determined blood BH4 and phenylalanine in two patients with hyperphenylalaninemia following oral load with BH4 10 mg/kg. Our patients underwent neonatal screening for PKU, had normal
Haruo, Shintaku, Hiroki, Fujioka, Yoshitomo, Sawada, Minoru, Asada, Tsunekazu, Yamano   +4 more
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