Results 41 to 50 of about 38,624 (185)

The Sponge-Derived Brominated Compound Aeroplysinin-1 Impairs the Endothelial Inflammatory Response through Inhibition of the NF-κB Pathway

Marine Drugs, 2022
(+)-Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that exhibits pleiotropic bioactive effects, impairing cell growth in cancer cells, inhibiting angiogenesis in vitro and in vivo and modulating the ...
Isabel Vidal, Laura Castilla, Ana Dácil Marrero, Inés Bravo-Ruiz, Manuel Bernal, Inmaculada Manrique, Ana R. Quesada, Miguel Ángel Medina, Beatriz Martínez-Poveda   +8 more
doaj   +1 more source

Aplicación de la Bioquímica y Biología Molecular en el Grado de Enfermería a través del aprendizaje basado en problemas [PDF]

, 2018
El CMD docente (CMD) se ha realizado en la asignatura de 1er curso “Bioquímica y Biología Molecular”. Se ha desarrollado incluyendo el temario correspondiente al bloque de Proteínas. Han participado 56 estudiantes.
Tous Rivera, Cristina
core   +1 more source

Stereochemical Modulation of Palladacyclopentadienyl Complexes Bearing Diphosphine Ligands: A Key to Enhanced DNA Interaction and Anticancer Activity

European Journal of Inorganic Chemistry, EarlyView.
A modular library of structurally robust palladacyclopentadienyl Pd(II) complexes bearing achiral and chiral diphosphines was developed, revealing a strong influence of diphosphine design and ligand chirality on cytotoxicity and selectivity against ovarian cancer cells, including platinum‐resistant models.
Stefania Mautone, Martina Scianna, Isabella Caligiuri, Laura Orian, Pablo Nogara, Nicola Demitri, Flavio Rizzolio, Thomas Scattolin   +7 more
wiley   +1 more source

Aumentando la presencia de la UCM en los MOOCs: Puesta en marcha de un curso online sobre neurociencia [PDF]

, 2017
Sección Deptal. de Bioquímica y Biología Molecular (Medicina)Fac.
De Lago Femia, Eva, Fernández Ruiz, José Javier, García García, María Concepción, Ramos Atance, José Antonio, Rodríguez Cueto, Carmen, Sagredo Esquioga, Onintza   +5 more
core   +1 more source

New evolving strategies revealed by transcriptomic analysis of a fur− mutant of the cyanotrophic bacterium Pseudomonas pseudoalcaligenes CECT 5344

Microbial Biotechnology, 2020
Summary The transcriptomic analysis (RNA‐seq) of a fur mutant of P. pseudoalcaligenes CECT 5344 has revealed that Fur regulates the expression of more than 100 genes in this bacterial strain, most of them negatively.
Gracia Becerra, María Isabel Igeño, Faustino Merchán, Rubén Sánchez‐Clemente, Rafael Blasco   +4 more
doaj   +1 more source

Bioquímica y biología molecular de las plantas [PDF]

, 2004
Si aplicamos un criterio antropocéntrico, las plantas superiores deben seguir de modo inmediato al hombre como objetos de interés tecnocientífico, ya que directa o indirectamente constituyen su principal sustento. Por otra parte, su papel central en la
García Olmedo, Francisco
core   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, EarlyView.
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source

Aryl Hydrocarbon Receptor: From Homeostasis to Tumor Progression

Frontiers in Cell and Developmental Biology, 2022
Transcription factor aryl hydrocarbon receptor (AHR) has emerged as one of the main regulators involved both in different homeostatic cell functions and tumor progression.
Claudia Rejano-Gordillo, Ana Ordiales-Talavero, Ana Nacarino-Palma, Jaime M. Merino, Francisco J. González-Rico, Pedro M. Fernández-Salguero   +5 more
doaj   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Deletion of C3G in hepatocytes impairs full liver maturation and alters glucose homeostasis

Cell Death and Disease
C3G (RapGEF1) regulates the biology of liver hepatic progenitor cells and hepatocarcinoma cells, but its role in hepatocytes remained unknown. Therefore, we generated a mouse model lacking C3G in hepatocytes (C3GKOAlb), which showed liver damage as ...
Nerea Palao, Jaime Mancebo, Cristina Baquero, Minerva Iniesta-González, Mateo Cueto-Remacha, María Rodrigo-Faus, Alvaro Gutierrez-Uzquiza, Paloma Bragado, Ángel M. Cuesta, Aránzazu Sánchez, Carmen Guerrero, Almudena Porras   +11 more
doaj   +1 more source