Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention [PDF]
, 2017 The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the hallmarks of cancer.
Carrillo, Paloma +7 more
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ChemSusChem, Volume 19, Issue 5, 13 March 2026.A sustainable chemo‐enzymatic synthesis of poly(cyclic carbonate)s from CO2 and renewable oils is reported for the first time using sponge‐like ionic liquids as reaction media by two sequential steps: epoxidation and CO2 cycloaddition. A sustainable chemo‐enzymatic synthesis of poly(cyclic carbonate)s from CO2 and renewable oils is reported for the ...
Francisco J. Ruiz +7 more
wiley +1 more source
GLS and GLS2 Glutaminase Isoenzymes in the Antioxidant System of Cancer Cells
AntioxidantsA pathway frequently altered in cancer is glutaminolysis, whereby glutaminase (GA) catalyzes the main step as follows: the deamidation of glutamine to form glutamate and ammonium.
Juan De los Santos-Jiménez +4 more
doaj +1 more source
Changes in P2Y Purinergic Receptor Expression in the Ciliary Body in a Murine Model of Glaucoma
Frontiers in Pharmacology, 2017 Glaucoma is a neuropathology, often accompanied by an elevated intraocular pressure (IOP), which can lead to blindness. Since DBA/2J mice develop glaucoma, several studies of the physiopathology of glaucoma have been reported in this animal model.
Begoña Fonseca +5 more
doaj +1 more source
Antitumor and antiangiogenic potential of solomonamide synthesis intermediates [PDF]
, 2017 Es comunicación (formato panel) a congreso internacionalIn this work we developed a new synthetic strategy towards the solomonamides. a novel class of cyclopeptides of marine origin. The described synthetic approach utilized an olefin metathesis reaction
Carrillo Fernandez, Paloma +6 more
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Structural basis of the allergenicity to strawberries due to Fra a 1.02 [PDF]
, 2018 Strawberry fruits are highly valued due to their flavor, aroma, and benefits for human health. Despite this, 30% of the population with food hypersensitivity also shows adverse reactions to strawberry (Franz-Oberdorf et al, 2016).
Casañal, Ana +8 more
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Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral Chagas disease in a patient with AIDS [PDF]
, 2005 Trypanosoma cruzi DNA was amplified from an intracranial biopsy and peripheral blood of an HIV patient with encephalitis; this episode was indicative of AIDS and congenital Chagas disease.
Altcheh, Jaime Marcelo +15 more
core +1 more source
Insights into aging mechanisms from comparative genomics in orange and silver roughies
Scientific ReportsThe demersal fish orange roughy (Hoplostethus atlanticus) can live for up to 250 years, twenty times more than its congener silver roughy (Hoplostethus mediterraneus). Studies of Hoplostethus have focused mainly on its ecology and conservation due to its
Dido Carrero +5 more
doaj +1 more source
Uridine Prevents Negative Effects of OXPHOS Xenobiotics on Dopaminergic Neuronal Differentiation
Cells, 2019 Neuronal differentiation appears to be dependent on oxidative phosphorylation capacity. Several drugs inhibit oxidative phosphorylation and might be detrimental for neuronal differentiation.
Eldris Iglesias +8 more
doaj +1 more source
NO3- selective mini-electrodes as a tool to investigate the NO3- traffic in Chlamydomonas reinhardtii D. [PDF]
, 2017 Ion selective NO3- mini-electrodes were used to measure the external NO3- concentration in C. reinhardtii liquid cultures. Electrodes were prepared using glass capillaries (1.5 mm external diameter).
Díaz, Jordi +4 more
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