Results 101 to 110 of about 182,780 (336)

Aeration and hydrodynamics in submerged membrane bioreactors [PDF]

open access: yes, 2011
Membrane bioreactor (MBR) is already a well-developed wastewater treatment process for both municipal and industrial applications. Nonetheless, membrane fouling remains a significant problem for its wider development.
Albasi, Claire   +3 more
core   +2 more sources

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

Investigating the removal of some pharmaceutical compounds in hospital wastewater treatment plants operating in Saudi Arabia [PDF]

open access: yes, 2016
The concentrations of 12 pharmaceutical compounds (atenolol, erythromycin, cyclophosphamide, paracetamol, bezafibrate, carbamazepine, ciprofloxacin, caffeine, clarithromycin, lidocaine, sulfamethoxazole and Nacetylsulfamethoxazol (NACS)) were ...
Akunna, Joseph C.   +3 more
core   +3 more sources

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

open access: yesAdvanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen   +11 more
wiley   +1 more source

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

open access: yesAdvanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu   +23 more
wiley   +1 more source

Integrating real-time OUR monitoring with adaptive feeding for enhanced antibody production

open access: yesBioresources and Bioprocessing
Background Fed-batch culture is a well-established and widely adopted platform for industrial antibody production using Chinese Hamster Ovary (CHO) cells. However, conventional fixed feeding strategies often fall short in meeting the dynamically changing
Xin-Ran Zhang   +6 more
doaj   +1 more source

Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium

open access: yesAdvanced Science, EarlyView.
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang   +3 more
wiley   +1 more source

Mini Bioreactor Can Support In Vitro Spermatogenesis of Mouse Testicular Tissue.

open access: green, 2022
Zahra Amirkhani   +3 more
openalex   +2 more sources

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Reconstruction of genome-scale metabolic model of Yarrowia lipolytica and its application in overproduction of triacylglycerol

open access: yesBioresources and Bioprocessing, 2017
Background Yarrowia lipolytica is widely studied as a non-conventional model yeast owing to the high level of lipid accumulation. Therein, triacylglycerol (TAG) is a major component of liposome. In order to investigate the TAG biosynthesis mechanism at a
Songsong Wei   +4 more
doaj   +1 more source

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