Results 91 to 100 of about 185,824 (352)

Investigating the removal of some pharmaceutical compounds in hospital wastewater treatment plants operating in Saudi Arabia [PDF]

, 2016
The concentrations of 12 pharmaceutical compounds (atenolol, erythromycin, cyclophosphamide, paracetamol, bezafibrate, carbamazepine, ciprofloxacin, caffeine, clarithromycin, lidocaine, sulfamethoxazole and Nacetylsulfamethoxazol (NACS)) were ...
Akunna, Joseph C., Al Qarni, Hamed M., Collier, Phillip, O'Keeffe, Juliette   +3 more
core   +3 more sources

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

The implementation of persuasive technology principles in mobile application development: a qualitative study [PDF]

, 2012
Preceding studies of persuasive technology have mentioned several benefits on the implementation of persuasive design features of the Persuasive System Design (PSD) model such as creating users' engagement and acceptance and continuous usage.
Abd Rahim, Mohd Hilmi Izwan, Goh, Kai Chen, Masrom, Md Asrul Nasid, Mohamed, Sulzakimin, Yunus, Riduan   +4 more
core   +3 more sources

Controlled diffusion processes with markovian switchings for modeling dynamical engineering systems [PDF]

, 2009
A modeling approach to treat noisy engineering systems is presented. We deal with controlled systems that evolve in a continuous-time over finite time intervals, but also in continuous interaction with environments of intrinsic variability. We face the
Cañada, Héctor, Romera, Rosario
core   +1 more source

Semicontinuous Bioreactor Production of Recombinant Butyrylcholinesterase in Transgenic Rice Cell Suspension Cultures. [PDF]

, 2016
An active and tetrameric form of recombinant butyrylcholinesterase (BChE), a large and complex human enzyme, was produced via semicontinuous operation in a transgenic rice cell suspension culture.
Corbin, Jasmine M, Hashimoto, Bryce I, Karuppanan, Kalimuthu, Kyser, Zachary R, McDonald, Karen A, Nandi, Somen, Noe, Amy R, Roberts, Brian A, Rodriguez, Raymond L, Wu, Liying   +9 more
core   +2 more sources

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

CRISPR–Cas9-mediated genomic multiloci integration in Pichia pastoris

Microbial Cell Factories, 2019
Background Pichia pastoris (syn. Komagataella phaffii) is a widely used generally recognized as safe host for heterologous expression of proteins in both industry and academia.
Qi Liu, Xiaona Shi, Lili Song, Haifeng Liu, Xiangshan Zhou, Qiyao Wang, Yuanxing Zhang, Menghao Cai   +7 more
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Integrating real-time OUR monitoring with adaptive feeding for enhanced antibody production

Bioresources and Bioprocessing
Background Fed-batch culture is a well-established and widely adopted platform for industrial antibody production using Chinese Hamster Ovary (CHO) cells. However, conventional fixed feeding strategies often fall short in meeting the dynamically changing
Xin-Ran Zhang, Qingyuan Ran, Botao Zhang, Yong-Mei He, Liang Zhao, Wen-Song Tan, Qian Ye   +6 more
doaj   +1 more source