Results 91 to 100 of about 81,744 (305)
Advanced Science, EarlyView.The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo +6 more
wiley +1 more source
CRISPR–Cas9-mediated genomic multiloci integration in Pichia pastoris
Microbial Cell Factories, 2019 Background Pichia pastoris (syn. Komagataella phaffii) is a widely used generally recognized as safe host for heterologous expression of proteins in both industry and academia.
Qi Liu +7 more
doaj +1 more source
Filtration characteristics of hollow fiber microfiltration membranes used in a specific double membrane bioreactor [PDF]
, 2009 The performance of the microfiltration in a specifically designed membrane bioreactor operating under various transmembrane pressures with periodic backwashing was investigated for model media.
Günther, Jan +2 more
core +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
Advanced Science, EarlyView.The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Cytoxicity and cytostatic drug removal in a membrane bioreactor from wastewater [PDF]
, 2009 The growing use of antineoplastic drugs in cancer therapy is an emerging issue in environmental research. The presence of the anticancer drug cyclophosphamide (CP) in municipal wastewater raises several environmental problems.
Delgado, Luis Fernando +6 more
core
Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
, 2013 Rotorua District Council constructed a membrane bioreactor (MBR) system to work in parallel with the existing Bardenpho system, to improve the overall capacity and removal efficiency of the wastewater treatment plant.
Rachmani, Asaf
core
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Biorreator à membrana de leito móvel em bateladas sequenciais para a remoção de nutrientes e matéria orgânica de efluentes sanitários [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Ambiental, Florianópolis, 2014.Este trabalho aborda o tratamento de efluentes sanitários considerando a remoção de nutrientes ...
Kellner, Ronaldo Luis
core
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source