Results 111 to 120 of about 71,391 (320)

Efficient gene deletion and replacement in Aspergillus niger by modified in vivo CRISPR/Cas9 systems

Bioresources and Bioprocessing, 2019
Aspergillus niger, as an important industrial strain, is widely used in the production of a variety of organic acids and industrial enzymes. To excavate the greater potential of A.
Yuan Zhang, Liming Ouyang, Yilin Nan, Ju Chu   +3 more
doaj   +1 more source

Monitoring management criterion of an anaerobic digester using an explicit model based on temperature and pH [PDF]

arXiv, 2017
In this paper, the stability analysis of an anaerobic digestion process is presented. The analysis is performed using a simplified mathematical model, which includes explicit temperature and pH dependence on kinetic growth rates. A detailed nonlinear and bifurcation analyses are performed in order to study the effects of temperature and pH parameters ...
arxiv  

A Novel 3D‐Printed Microfluidic Bioreactor With Electrospun Scaffold Integration as a Platform for Cardiovascular Tissue Engineering

Journal of Applied Polymer Science, EarlyView.
ABSTRACT Cardiovascular diseases are one of the leading causes of global mortality. Treatment methods such as bypass graft operations, while often successful, can fail in cases of systemic disease or compliance mismatch. Tissue engineered vascular grafts may offer a potential solution, by means of an implantable cell‐seeded scaffold that can integrate ...
Andrew P. Johnston, Todd P. Burton, Anthony Callanan   +2 more
wiley   +1 more source

Rapid isolation and quantification of extracellular vesicles from suspension‐adapted human embryonic kidney cells using capillary‐channeled polymer fiber spin‐down tips

ELECTROPHORESIS, Volume 44, Issue 1-2, Page 190-202, January 2023., 2023
Abstract Exosomes, a subset of extracellular vesicles (EVs, 30–200‐nm diameter), serve as biomolecular snapshots of their cell of origin and vehicles for intercellular communication, playing roles in biological processes, including homeostasis maintenance and immune modulation.
Kaylan K. Jackson, R. Kenneth Marcus
wiley   +1 more source

Controlling temperature by direct liquid–liquid heat exchange in continuous bioreactors [PDF]

, 1981
Emil Wick
openalex   +1 more source

Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo, Luz María Martínez, Noemí Flores, Georgina Hernández‐Chávez, Fernanda Cueto, Alfredo Martinez, Rosa Isela Corona‐González, Guillermo Gosset   +7 more
wiley   +1 more source

Influence of oxygen concentration on the metabolism of Penicillium chrysogenum

Engineering in Life Sciences, Volume 23, Issue 1, January 2023., 2023
Abstract In large‐scale bioreactors, there is often insufficient mixing and as a consequence, cells experience uneven substrate and oxygen levels that influence product formation. In this study, the influence of dissolved oxygen (DO) gradients on the primary and secondary metabolism of a high producing industrial strain of Penicillium chrysogenum was ...
Agnes Janoska, Jelle J. Verheijen, Wenjung Tang, Queenie Lee, Baukje Sikkema, Walter M. van Gulik   +5 more
wiley   +1 more source

Kalman-based approaches for online estimation of bioreactor dynamics from fluorescent reporter measurements [PDF]

arXiv
We address online estimation of microbial growth dynamics in bioreactors from measurements of a fluorescent reporter protein synthesized along with microbial growth. We consider an extended version of standard growth models that accounts for the dynamics of reporter synthesis. We develop state estimation from sampled, noisy measurements in the cases of
arxiv  

The role of Moringa oleifera in the development of alternative biofuels, under the concept of an integral one‐tree biorefinery: A minireview

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The Moringa oleifera oil tree is commonly known as the ‘tree of life’ or the ‘miracle tree’ owing to its multiple benefits for humans. The different parts that make up this tree (leaves, seeds and bark) have been used to treat various ailments, diseases and wounds. However, in recent years this tree is being used by the scientific community to
J. L. Aleman‐Ramirez, Patrick U. Okoye, S. Saldaña‐Trinidad, S. Torres‐Arellano, P. J. Sebastian   +4 more
wiley   +1 more source

Insights into Streptomyces coelicolor A3(2) growth and pigment formation with high‐throughput online monitoring

Engineering in Life Sciences, Volume 23, Issue 1, January 2023., 2023
Abstract Streptomyces species are intensively studied for their ability to produce a variety of natural products. However, conditions influencing and leading to product formation are often not completely recognized. Therefore, in this study, high‐throughput online monitoring is presented as a powerful tool to gain in‐depth understanding of the ...
Maurice Finger, Fabio Sentek, Lukas Hartmann, Ana M. Palacio‐Barrera, Ivan Schlembach, Miriam A. Rosenbaum, Jochen Büchs   +6 more
wiley   +1 more source