Results 111 to 120 of about 72,831 (298)

Improvement of ribonucleic acid production in Cyberlindnera jadinii and optimization of fermentation medium

AMB Express
To enhance the ribonucleic acid (RNA) productivity for industrial applications, this study employed strain screening and medium optimization to improve the content of RNA in Cyberlindnera jadinii.
Mengting Li, Shuhong Gao, Pengcheng Yang, Hejin Li   +3 more
doaj   +1 more source

Immobilization of Trichoderma viride cellulase and its application to a bioreactor.

, 1986
Nobuyuki NOZAKI, Hideyuki NAKAGAWA, Yutaka Kashiwagi, Yumi Magae, Takashi Sasaki   +4 more
openalex   +2 more sources

Scale‐Down Analysis of Fouling in Cell Retention Devices for the Continuous Production of Monoclonal Antibodies

Journal of Advanced Manufacturing and Processing, EarlyView.
ABSTRACT The use of perfusion bioreactor systems is increasing in biomanufacturing due to their potential for productivity gains, increased facility utilization, and process intensification. Systematic studies on cell retention devices are limited even if these devices are often described as process‐limiting during perfusion.
Delphine Tavernier, Timothy Erlandson, Andrea C. M. E. Rayat   +2 more
wiley   +1 more source

Enhanced Exosome Production in Mesenchymal Stem Cells via Extracellular Matrix‐Incorporated 3D Spheroid Printing

Advanced NanoBiomed Research, EarlyView.
A novel extracellular matrix (ECM)‐integrated mesenchymal stem cell spheroid bioprinting technology has been introduced to significantly enhance exosome production for therapeutic applications. By optimizing spheroid size and ECM composition, the study demonstrates an 18.4‐fold increase in exosome yield compared to 2D culture systems.
Jun‐Ho Heo, Min Kyeong Kim, Sang Jin Lee, Hyun‐Wook Kang   +3 more
wiley   +1 more source

Harnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts

Advanced NanoBiomed Research, EarlyView.
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael, Yuen Ting Lam, Timothy C. Mitchell, Miguel Santos, Alex H. P. Chan, Xinying Liu, Angus J. Grant, Matthew J. Moore, David F. Fletcher, Richard P. Tan, Steven G. Wise   +10 more
wiley   +1 more source

Design and Application of Piezoelectric Conductive Smart Scaffold for Noninvasive Neural Tissue Regeneration via Custom‐Made In Vitro Mechano‐Stimulator

Advanced NanoBiomed Research, EarlyView.
Schematic illustration showing the design of the developed invitro mechano stimulator (IMS) and the electrospun nanofiber‐based piezoelectric and conductive nerve conduit (PCNC) that can self‐generate electrical stimulations analogous to neural tissues. IMS provided vital electrical cues for the neural cells to attach, align and proliferate on the PCNC
Afeesh Rajan Unnithan, Vignesh Krishnamoorthi Kaliannagounder, Nagamalleswara Rao Alluri, Chan Hee Park, Pandiyarasan Veluswamy, Arathyram Ramachandra Kurup Sasikala   +5 more
wiley   +1 more source

Optimization of oxygen transfer and power consumption in aerobic bioprocess by designing disc turbine impeller based on CFD-Taguchi method

Scientific Reports
Disc turbine impeller serves as a vital component of stirred-tank bioreactors and plays crucial role in optimizing their performance. This research integrates Computational Fluid Dynamics (CFD) with Taguchi experimental method to analyze the effects of ...
Qingfeng Gu, Sainan Yang, Ali Mohsin, Junxiong Yu, Yingping Zhuang, Chao Li   +5 more
doaj   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source

Some Characteristics of Continuous Glycerolysis of Fat by Lipase with Microporous Membrane Bioreactor

, 1987
Tsuneo Yamané, Joon Shick Rhee, Yoshifumi Ohta, Shoichi Shimizu   +3 more
openalex   +2 more sources

Contrastive-learning of language embedding and biological features for cross modality encoding and effector prediction

Nature Communications
Identifying and characterizing virulence proteins secreted by Gram-negative bacteria are fundamental for deciphering microbial pathogenicity as well as aiding the development of therapeutic strategies.
Yue Peng, Junze Wu, Yi Sun, Yuanxing Zhang, Qiyao Wang, Shuai Shao   +5 more
doaj   +1 more source