Results 61 to 70 of about 182,780 (336)

Mapping molecular pathways for embryonic Sertoli cells derivation based on differentiation model of mouse embryonic stem cells

open access: yesStem Cell Research & Therapy, 2020
Background Embryonic Sertoli cells (eSCs) have been known for playing important roles in male reproductive development system. In current studies, eSCs were mainly generated from induced intermediate mesoderm.
Chenze Xu   +5 more
doaj   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak   +6 more
wiley   +1 more source

Development of an economical fermentation platform for enhanced ansamitocin P-3 production in Actinosynnema pretiosum

open access: yesBioresources and Bioprocessing, 2019
Background Ansamitocin P-3 (AP-3), produced by Actinosynnema pretiosum, has extraordinary antitumor activity and has been used as toxic “warhead” in antibody-conjugated drugs. However, AP-3 production is limited by its low yield and thus the high cost of
Ting Liu   +4 more
doaj   +1 more source

A novel temporary immersion bioreactor system for large scale multiplication of banana (Rasthali AAB—Silk)

open access: yesScientific Reports, 2021
Musa sp. cultivar Rasthali (Silk AAB) is a choice variety of the Asian sub-continent. Its production and sustenance are threatened by Fusarium wilt, which affects the livelihoods of small and marginal farmers.
Subbaraya Uma   +4 more
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

Effect of cytostatic drug presence on extracellular polymeric substances formation in municipal wastewater treated by membrane bioreactor [PDF]

open access: yes, 2010
The effect of the cyclophosphamide and its mean metabolites on extracellular polymeric substances (EPS) formation was investigated. Two lab-scale membrane bioreactors were followed in parallel (one with the cytostatic drugs, the second without ...
Albasi, Claire   +5 more
core   +4 more sources

A Patient‐Specific 3D Printed Carotid Artery Model Integrating Vascular Structure, Flow, and Endothelium Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces the first miniaturized, patient‐specific carotid artery model created via 3D printing using GelMA with embedded vascular cells. Combining CFD, PIV, and flow perfusion, the model replicates anatomically dependent hemodynamics and cellular responses.
Jorge A. Catano   +7 more
wiley   +1 more source

Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system

open access: yesBioresources and Bioprocessing, 2022
Background β-Nicotinamide mononucleotide (NMN) is the direct precursor of nicotinamide coenzymes such as NAD+ and NADP+, which are widely applied in industrial biocatalysis especially involving cofactor-dependent oxidoreductases.
Xiao-Long Qian   +5 more
doaj   +1 more source

Dynamical Modelling and Simulation of Waste water Filtration Process by Submerged Membrane Bioreactors [PDF]

open access: yes, 2009
A mathematical model was developed for the filtration process and the influence of aeration on Submerged Membrane Bioreactors. The dynamics of sludge attachment to and detachment from the membrane, in relation to the filtration and a strong intermittent ...
Albasi, Claire   +3 more
core   +2 more sources

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

open access: yesAdvanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan   +3 more
wiley   +1 more source

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