Results 71 to 80 of about 72,831 (298)

Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D‐Printed Titanium Truss

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee   +9 more
wiley   +1 more source

Bioreactors in Hungary

open access: yesActa Agraria Debreceniensis, 2005
The transformation and utilization of organic materials must occur with the highest degree of environmental conformity. This conformity – in accordance with the guiding principles of the European Union – will result in a new economic and systematical approach.
Stephan Maniak, Botond Sinóros-Szabó
openaire   +3 more sources

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim   +7 more
wiley   +1 more source

Competition between biodetoxification fungus and lactic acid bacterium in the biorefinery processing chain for production of cellulosic L-lactic acid

open access: yesBioresources and Bioprocessing
Biodetoxification fungus selectively degrades toxic inhibitors generated from pretreatment of lignocellulose without consuming fermentable sugars.
Zhibin Li   +4 more
doaj   +1 more source

Cooperation of FGF/MEK/ERK and Wnt/β-catenin pathway regulators to promote the proliferation and pluripotency of mouse embryonic stem cells in serum- and feeder-free conditions

open access: yesBioresources and Bioprocessing, 2019
The FGF/MEK/ERK and Wnt/β-catenin signaling pathways have previously been proved to regulate mouse embryonic stem cell (mESCs) function. However, the relationships between these two pathways, especially their different functions on proliferation and ...
Tong Zhang   +5 more
doaj   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

open access: yesAdvanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong   +8 more
wiley   +1 more source

A Photonastic Prototissue Capable of Photo‐Mechano‐Chemical Transduction

open access: yesAdvanced Materials, EarlyView.
Mimicking energy transduction in prototissue assemblies remains a challenge of bottom‐up synthetic biology. In this work, prototissues integrating protocells with photothermal gold nanoparticle proto‐organelles and a thermoresponsive polymeric proto‐cortex are developed.
Agostino Galanti   +7 more
wiley   +1 more source

A Microfluidic Multiplex Sorter for Strain Development

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves   +6 more
wiley   +1 more source

The smallest bioreactor [PDF]

open access: yesNature Methods, 2005
A method for encapsulating single cells or single organelles in aqueous droplets combines optical trapping and microfluidic droplet generation techniques.
openaire   +1 more source

Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids in Bioreactor Headspaces Using a Nanomechanical Sensor

open access: yesAdvanced Materials Technologies, EarlyView.
A porous crystalline sensing layer has been developed in conjunction with a nanomechanical sensor for the sensitive detection of volatile fatty acids (VFAs) in admixture at high relative humidity. The sensitive, selective sensor based on supramolecular design improves the economic viability of anaerobic digesters toward a carbon neutral society ...
Subrata Maji   +13 more
wiley   +1 more source

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