Scale-Up Transformed Shoot and Hairy Root Cultures of Salvia bulleyana in Bioreactor Systems: Process Optimization and Metabolite Productivity [PDF]
MoleculesTo ensure large-scale production of plant-derived polyphenols, efficient and scalable in vitro culture systems are needed that can enable high biomass accumulation and secondary metabolite biosynthesis.
Marta Krzemińska +3 more
doaj +2 more sources
Hierarchical Flux-Protection Engineering Stabilizes Oxidation-Prone Metabolic Nodes for High-Level Curcumin Biosynthesis. [PDF]
Adv Sci (Weinh)Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Chen J +10 more
europepmc +2 more sources
Stem cell expansion and bioreactor development [PDF]
, 2010 PhDA major challenge to the clinical success of cell-based tissue engineering strategies is the ability to obtain sufficient numbers of cells within an acceptable time frame.
Ramlogan, Anil Shiva
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Technology in Horticulture, 2023 Various bioreactors, using temporary immersion systems (TIS) based on different designs and working principles, can have positive effects on development and multiplication of plantlets during micropropagation.
John L. Griffis Jr +3 more
doaj +1 more source
Design of a bubble-swarm bioreactor for animal cell culture [PDF]
, 1994 Gudermann F, Lütkemeyer D, Lehmann J. Design of a bubble-swarm bioreactor for animal cell culture. Cytotechnology. 1994;15(1-3):301-309.A stationary bubble-swarm has been used to aerate a mammalian cell culture bioreactor with an extremely low gas flow ...
Lehmann, Jürgen +2 more
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Chemical Engineering Transactions, 2014 The objective of this study was to investigate the hydrogen and methane production from cassava wastewater by using a two stage upflow anaerobic sludge blanket (UASB) system under thermophillic operation (55 °C).
P. Intanoo, E. Gulari, S. Chavadej
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Cellulase Production by Aspergillus niger ATCC 16888 on Copra Waste from Coconut Milk Process In Layered Packed-bed Bioreactor [PDF]
Chemical and Biochemical Engineering Quarterly, 2018 Solid-state fermentation (SSF) has been used to produce value-added products from agricultural and food processing wastes, but the majority of SSF production has been conducted on a small scale due to the limitations of heat and mass transfer.
T. Chysirichote
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Effect of cytostatic drugs on microbial behaviour in membrane bioreactor system [PDF]
, 2010 The aim of this work is to evaluate the influence of cyclophosphamide and its principal metabolites (CPs) on microbial behaviour in a membrane bioreactor system. Two laboratory-scale membrane bioreactors (MBR) were run in parallel with a sludge retention
Delgado, Luis Fernando +3 more
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Productivity enhancement in L-lysine fermentation using oxygen-enhanced bioreactor and oxygen vector
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: L-lysine is a bulk product. In industrial production using high-biomass fermentation, the high density of bacteria and the intensity of production require sufficient cellular respiratory metabolism for support.
Jinduo Wang +11 more
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Biological treatment and thickening with a hollow fibre membrane bioreactor [PDF]
, 2014 Aerobic operation of an immersed hollow fibre membrane bioreactor, treating municipal wastewater supplemented with molasses solution, has been studied across mixed liquor suspended solids (MLSS) concentrations between 8 and 32 g L-1, the higher ...
Connery, Karen A. +6 more
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