Results 151 to 160 of about 30,448 (259)

Bioreactor

Sen'i Gakkaishi, 1991
openaire   +2 more sources

Evaluation of Different Bioreactors During In Vitro Shoot Proliferation and Acclimatization of Agave (<i>Agave marmorata</i> Roezl). [PDF]

Plants (Basel)
Moreno-Hernández MDR, Mancilla-Álvarez E, López-Buenfil JA, Bello-Bello JJ.   +3 more
europepmc   +1 more source

Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP)

Biotechnology Progress, EarlyView.
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi, Nate Heller, Mohammadreza Ahmadimashhadi, Jon Petrone, Nicholas Marchand, Siavash Darvishmanesh, Ka Zhang, Stefano Menegatti, Andrew L. Zydney   +8 more
wiley   +1 more source

Co-Expression and Co-Purification Enable Manufacturing of a Six-Monoclonal Antibody Botulinum Antitoxin Cocktail. [PDF]

Toxins (Basel)
Davis A, Bajwa K, Martinez Z, Davis RR, Green A, Suber F, Farr-Jones S, Tomic MT.   +7 more
europepmc   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Bioreactor expansion of human neural progenitor cells for exosome scalable production and miRNA-engineering. [PDF]

J Biol Eng
Corraliza-Gomez M, Ianni M, Nogueira DES, Salvador WOS, Miguéis M, Garcia-Alloza M, Rodrigues CAV, Cabral JMS, Brites D.   +8 more
europepmc   +1 more source

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

Biotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera, Ivan Gajic, Praveen Kusumanchi, Angela Andaluz, Gabrielle Dela Pena, Clifford A. Froelich, Elizabeth Higgins, Jennifer Johnston, Seyed Pouria Motevalian   +8 more
wiley   +1 more source

Modeling and validating of oxygen transport in wave bioreactors: optimized experimental mass transfer method and novel Lattice-Boltzmann CFD approach. [PDF]

Front Bioeng Biotechnol
Piontek S, Fitschen J, Weiland C, Habicher T, Schlüter M, Wucherpfennig T.   +5 more
europepmc   +1 more source

Economic and environmental implications of the development of UASB reactors in Mexico for sustainable industrial wastewater treatment

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The objective of this work is to demonstrate that the inclusion of an up‐flow anaerobic sludge bed (UASB reactor) within an industrial wastewater treatment plant reduces the plant's investment and operating costs compared to a system based solely on conventional complete‐mix activated sludge (CMAS), operating under the same design principles ...
Juan Manuel Morgan‐Sagastume, Adalberto Noyola   +1 more
wiley   +1 more source

Reactor engineering for the enzymatic synthesis of 5-hydroxymethylfurfural stearate in a batch bioreactor and a packed bed flow bioreactor. [PDF]

Bioresour Bioprocess
Guajardo N, Gajardo-Parra N, Cea-Klapp E, Canales R, Lienqueo ME, Sandoval G.   +5 more
europepmc   +1 more source