Results 21 to 30 of about 30,448 (259)

Cancer Exosomes: An Overview and the Applications of Flow

Fluids, 2022
Cancer is one of the most prevalent and disruptive diseases affecting the population, and as such, is the subject of major research efforts. Recently, these efforts have been put towards understanding the role that exosomes can play in the progression of
Parker Bryant, Vassilios I. Sikavitsas
doaj   +1 more source

Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity

Frontiers in Bioengineering and Biotechnology
IntroductionViola odorata is a medicinal plant used in the indigenous systems of medicine in India, to treat respiratory tract disorders. V. odorata natural plant source is limited in availability.
R. Babu, Manokaran Veeramani, Wallepure Aadinath, Vignesh Muthuvijayan, Shailja Singh, Smita Srivastava   +5 more
doaj   +1 more source

Multispecies Bacterial Biofilms and Their Evaluation Using Bioreactors

Foods, 2023
Pathogenic biofilm formation within food processing industries raises a serious public health and safety concern, and places burdens on the economy.
Grishma S. Prabhukhot, Charles D. Eggleton, Jitendra Patel   +2 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Reflecting on Mechanical Functionalities in Bioreactors for Tissue Engineering Purposes

International Journal of Technology, 2020
Many articles have reported a correlation between the use of mechanical stimulation and an enhancement in cultivation of various tissues engineered in bioreactors.
Muhammad Hanif Nadhif, Hanif Assyarify, Affan Kaysa Waafi, Yudan Whulanza   +3 more
doaj   +1 more source

The Colourimetric Method for Mixing Time Measurement in Single-Use and Multi-Use Bioreactors—Methodology Overview and Practical Recommendations

Energies, 2023
Mixing time is an important parameter for quantifying the mixing efficiency of a bioreactor system, essential for successful bioprocess development in various branches of the bioengineering sector (e.g., biopharma, biorefineries, food industry and ...
Mateusz Bartczak, Maciej Pilarek
doaj   +1 more source

Artery‐on‐Chip Demonstrates Mechanical and Functional Features of Healthy and Diseased Living Smooth Muscle Tissue

Advanced Functional Materials, EarlyView.
This article details the development of an artery‐on‐chip platform for in vitro arterial disease modeling and therapeutic discovery. It describes the fabrication of a fibrin biomaterial scaffold seeded with iPSC‐derived smooth muscle and endothelial cells, mimicking native artery properties. Two genetic disease models showcase the platform's ability to
Danielle Yarbrough, Roy Chen, Katerina Katsouleas, Jaron Shoemaker, Travis Brady, Tianfang Yu, Jennifer Arthur Ataam, Connor Amelung, Lakshmi Santhanam, Ioannis Karakikes, Sharon Gerecht   +10 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

Advanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher, Joachim Schenk, Alessandro Cianciosi, Katherina Hemmen, David Böhringer, Franziska Dusi, Jessica Faber, Philipp Stahlhut, Benedikt Gantert, Emilie Rouenhoff, Annika Gmöhling, Tessa Lühmann, Jörg Teßmar, Jürgen Groll, Silvia Budday, Tomasz Jüngst, Ben Fabry, Katrin G. Heinze, Petra Bauer‐Kreisel, Torsten Blunk   +19 more
wiley   +1 more source

Human tendon stem/progenitor cell-derived extracellular vesicle production promoted by dynamic culture

Artificial Cells, Nanomedicine, and Biotechnology
Tendon injuries significantly impact quality of life, prompting the exploration of innovative solutions beyond conventional surgery. Extracellular Vesicles (EVs) have emerged as a promising strategy to enhance tendon regeneration.
Marta Clerici, Maria Camilla Ciardulli, Erwin Pavel Lamparelli, Joseph Lovecchio, Emanuele Giordano, Tina P. Dale, Nicholas R. Forsyth, Nicola Maffulli, Giovanna Della Porta   +8 more
doaj   +1 more source