Results 51 to 60 of about 111,398 (363)
Macro-scale Topology Optimization for Controlling Internal Shear Stress in a Porous Scaffold Bioreactor [PDF]
Biotechnology & Bioengineering, 109(7):1844-1854 (2012), 2011 Shear stress is an important physical factor that regulates proliferation, migration and morphogenesis. In particular, the homeostasis of blood vessels is dependent on shear stress. To mimic this process ex vivo, efforts have been made to seed scaffolds with vascular and other cell types in the presence of growth factors and under pulsatile flow ...
arxiv +1 more source
CFD modeling of a fixed-bed biofilm reactor coupling hydrodynamics and biokinetics [PDF]
, 2016 Peer ReviewedPostprint (author's final ...
Chiva, Sergio +5 more
core +2 more sources
Biotechnology Journal, Volume 18, Issue 1, January 2023., 2023 Graphical Abstract and Lay Summary The heterogenous production conditions in large‐scale bioreactors cause scale‐up problems, such as reduced biomass or product yield, to occur during bioprocesses. In this study, we designed a two‐compartment scale‐down reactor and used it to simulate large‐scale heterogenous production conditions, allowing us to ...
Florian Mayer +7 more
wiley +1 more source
The cost of a large-scale hollow fibre MBR [PDF]
, 2010 A cost sensitivity analysis was carried out for a full-scale hollow fibre membrane bioreactor to quantify the effect of design choices and operational parameters on cost.
Brepols, Christoph +4 more
core +1 more source
Dimensionnement et extrapolation des bioréacteurs sur base de paramètres physiologiques : cas de la production de lipase par Yarrowia lipolytica [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2011 Bioreactor scale-up and design on the basis of physiologically relevant parameters: application to the production of lipase by Yarrowia lipolytica.
Kar, T. +3 more
doaj
Effect of cytostatic drugs on microbial behaviour in membrane bioreactor system [PDF]
, 2010 The aim of this work is to evaluate the influence of cyclophosphamide and its principal metabolites (CPs) on microbial behaviour in a membrane bioreactor system. Two laboratory-scale membrane bioreactors (MBR) were run in parallel with a sludge retention
Albasi, Claire +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.Laboratory protocols for producing thin‐film pH electrodes for sterilized single‐use technologies have been successfully developed into a semiautomated workflow, with higher throughput and precision of membrane thickness. Accuracies are within 0.05 pH units versus ground truth, and uncertainty analysis reveals the largest sources of error to be derived
Bingyuan Zhao +4 more
wiley +1 more source
Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates. [PDF]
, 2020 Cell-derived extracellular matrix (ECM) provides a niche to promote osteogenic differentiation, cell adhesion, survival, and trophic factor secretion.
Genetos, DC +6 more
core
Dynamical Modelling and Simulation of Waste water Filtration Process by Submerged Membrane Bioreactors [PDF]
, 2009 A mathematical model was developed for the filtration process and the influence of aeration on Submerged Membrane Bioreactors. The dynamics of sludge attachment to and detachment from the membrane, in relation to the filtration and a strong intermittent ...
Albasi, Claire +3 more
core +2 more sources
Advanced Functional Materials, EarlyView.In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García +23 more
wiley +1 more source