Modulation of the cardiomyocyte contraction inside a hydrostatic pressure bioreactor: $\textit{in vitro}$ verification of the Frank-Starling law [PDF]
BioMed Research International 2015;2015:542105, 2019 We have studied beating mouse cardiac syncytia $\textit{in vitro}$ in order to assess the inotropic, ergotropic, and chronotropic effects of both increasing and decreasing hydrostatic pressures. In particular, we have performed an image processing analysis to evaluate the kinematics and the dynamics of those pressure-loaded beating syncytia starting ...
arxiv +1 more source
Towards synthetic biological approaches to resource utilization on space missions. [PDF]
, 2015 This paper demonstrates the significant utility of deploying non-traditional biological techniques to harness available volatiles and waste resources on manned missions to explore the Moon and Mars. Compared with anticipated non-biological approaches, it
Arkin, Adam P +3 more
core +2 more sources
Ammonia Dynamics in the Human Body: Insights in Biomedical Sensing Technologies
Advanced Sensor Research, EarlyView.Ammonia (NH3) is a significant biomarker in diagnostics, affecting the respiratory system, stomach, liver, kidneys, bladder, and gastrointestinal tract. NH3 detection, using sensors, has the potential to improve medical diagnosis. This review examines recent advancements in NH3 sensing technologies and explores future research directions, including ...
Annelot Nijkoops +8 more
wiley +1 more source
In vitro culture of sweet basil: gas exchanges, growth, and rosmarinic acid production
Biologia Plantarum, 2014 Five in vitro culture systems with different ventilation rates were used to investigate the influence of vessel environment on photosynthesis, dark respiration, ethylene evolution, and rosmarinic acid (RA) production in sweet basil (Ocimum basilicum L ...
C. Kiferle +4 more
doaj +1 more source
Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration
Advanced Therapeutics, EarlyView.Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana +5 more
wiley +1 more source
Hepatocyte Aggregates: Methods of Preparation in the Microgravity Simulating Bioreactor Use in Tissue Engineering [PDF]
arXiv, 2008 Tissue Engineering concerns the three-dimensional cell growth so that bio-artificial tissues could be created and used for transplantation. The recently expressed concerns from the Tissue Engineering research community for a re-direction of the research activities necessitate the proposition of new methodologies. We propose a methodology that has to do
arxiv
Data-driven and Physics Informed Modelling of Chinese Hamster Ovary Cell Bioreactors [PDF]
arXiv, 2023 Fed-batch culture is an established operation mode for the production of biologics using mammalian cell cultures. Quantitative modeling integrates both kinetics for some key reaction steps and optimization-driven metabolic flux allocation, using flux balance analysis; this is known to lead to certain mathematical inconsistencies.
arxiv
Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture [PDF]
, 2016 Tissue culture has been used for over 100 years to study cells and responses ex vivo. The convention of this technique is the growth of anchorage dependent cells on the 2-dimensional surface of tissue culture plastic.
Ellis, MJ +7 more
core +1 more source
Computational fluid dynamic analysis of bioprinted self-supporting perfused tissue models [PDF]
, 2020 Natural tissues are incorporated with vasculature, which is further integrated with a cardiovascular system responsible for driving perfusion of nutrient‐rich oxygenated blood through the vasculature to support cell metabolism within most cell‐dense ...
Bonewald, Lynda F. +8 more
core +1 more source
Developing Quorum Sensing‐Based Collaborative Dynamic Control System in Halomonas TD01
Advanced Science, EarlyView.A standardized and streamlined inducer‐free quorum sensing (QS)‐based collaborative dynamic control pattern is developed for sufficient gene expression control in Halomonas TD by mixing two engineered cells, cells A and B. Proof‐of‐concept studies are designed to test the dynamic control performance in mixed cultures in fed‐batch conditions.
Yi‐Na Lin +12 more
wiley +1 more source