Results 81 to 90 of about 120,525 (339)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System

Frontiers in Cell and Developmental Biology, 2020
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based therapies due to their multilineage differentiation potential and intrinsic immunomodulatory and trophic activities.
Miguel de Almeida Fuzeta, Miguel de Almeida Fuzeta, Nuno Bernardes, Filipa D. Oliveira, Ana Catarina Costa, Ana Fernandes-Platzgummer, José Paulo Farinha, Carlos A. V. Rodrigues, Sunghoon Jung, Rong-Jeng Tseng, William Milligan, Brian Lee, Miguel A. R. B. Castanho, Diana Gaspar, Joaquim M. S. Cabral, Cláudia Lobato da Silva   +15 more
doaj   +1 more source

Investigating the significance of coagulation kinetics on maintaining membrane permeability in an MBR following reactive coagulant dosing [PDF]

, 2016
In this study, the impact of kinetically controlled floc growth on sustaining membrane permeability following reactive coagulant dosing was determined using a model particle system.
Autin, Oliver, Hai, F., Judd, Simon J., McAdam, Ewan J.   +3 more
core   +1 more source

Engineering Anisotropic Mechanical Properties in Large‐Scale Fabricated Cartilage Constructs Using Microfiber Reinforcement

Advanced Healthcare Materials, EarlyView.
This study presents the development of large‐scale (15 cm2) cartilage constructs with anisotropic mechanical properties using melt electrowritten (MEW) microfiber reinforced cell‐laden gelatin methacryloyl (gelMA). These constructs mimic the mechanical behavior of native cartilage, providing a suitable environment for Articular Cartilage ...
Lennard Spauwen, Alba Pueyo Moliner, Patrick van Veenendaal, Roel Custers, Jos Malda, Mylène de Ruijter   +5 more
wiley   +1 more source

Electromagnetic Stirring in a Microbioreactor with Non-conventional Chamber Morphology and Implementation of Multiplexed Mixing [PDF]

, 2015
© 2015 The Authors. Journal of Chemical Technology & Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. This is an open access article under the terms of the Creative Commons Attribution License, which permits use,
Andersson, Bolić, Buchenauer, Chen, Clime, Davies, Derby, Doran, Good, Good, Hessel, Hortsch, Kirk, Lee, Lee, Lee, Li, Maharbiz, Meijer, Rodriguez, Rodriguez, Rohe, Samorski, Schäpper, Schäpper, Szita, Vulto   +26 more
core   +2 more sources

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Microalgae for municipal wastewater nutrient remediation: mechanisms, reactors and outlook for tertiary treatment [PDF]

, 2015
This review explores the use of microalgae for nutrient removal in municipal wastewater treatment, considering recent improvements in the understanding of removal mechanisms and developments of both suspended and non-suspended systems.
Bogan R, Choi HJ, Craggs RJ, Gates W, Laliberté G, Larsdotter K, Li Y, Oh-Hama T, Oswald WJ, Picot B, Rhee G, Schumacher G, Thimijan RW, Yeh N   +13 more
core   +2 more sources

Microtechnology in Space Bioreactors

CHIMIA, 1999
Space biology is a young and rapidly developing discipline comprising basic research and biotechnology. In the next decades it will play a prominent role in the International Space Station (ISS). Therefore, there is an increasing demand for sophisticated instrumentation to satisfy the requirements of the future projects in space biology.
Isabelle Walther, Bart van der Schoot, Marc Boillat, Otfried Müller, Augusto Cogoli   +4 more
openaire   +4 more sources

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha, Sneha Kollenchery Ramanathan, Kristin Oskarsdotter, Fatemeh Rasti Boroojeni, Aleksandra Zielińska, Sajjad Naeimipour, Philip Lifwergren, Nina Reustle, Lauren Roberts, Annika Starkenberg, Gunnar Kratz, Peter Apelgren, Karin Säljö, Jonathan Rakar, Lars Kölby, Daniel Aili, Johan Junker   +16 more
wiley   +1 more source

Investigation of Aeration Rate on Uranium Bioleaching in Internal Airlift Bioreactor [PDF]

مجله علوم و فنون هسته‌ای, 2012
Uranium is leached from the uranium ore of the second anomaly of Saghand by the Acidithiobacillus ferrooxidans bacteria in an internal airlift bio-reactor. This study has been made to find the effect of aeration rate as well as its optimal value.
M.R Zolala, S.J Safdari, A Haghighi Asl, A Rashidi   +3 more
doaj