Results 141 to 150 of about 4,221 (165)

Advancing the Harmonization of Biopredictive Methodologies through the Product Quality Research Institute (PQRI) Consortium: Biopredictive Dissolution of Dipyridamole Tablets. [PDF]

Mol Pharm
Tsume Y, Ashworth L, Bermejo Sanz M, Cicale V, Dressman J, Fushimi M, Gonzalez-Alvarez I, Haung PS, Jankovsky C, Liu X, Lu X, Matsui K, Patel S, Ruiz-Picazo A, Sun CC, Thakral N, Zöller L.   +16 more
europepmc   +1 more source

Unlocking radical reactivity of cyclic diaryl λ³-chloranes through NHC-catalyzed three-component coupling. [PDF]

Chem Sci
Kunhiraman AA, Patra K, Kumar Choutipalli VS, Godara M, Shuford KL, Baidya M.   +5 more
europepmc   +1 more source

Integrating In Vitro Dissolution and Physiologically Based Pharmacokinetic Modeling for Generic Drug Development: Evaluation of Amorphous Solid Dispersion Formulations for Tacrolimus. [PDF]

Pharmaceutics
Karakitsios E, Angelerou MF, Kapralos I, Tsakiridou G, Kalantzi L, Dokoumetzidis A.   +5 more
europepmc   +1 more source

Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and its Regulatory Utility to Support Oral Drug Product Development and Harmonization. [PDF]

Pharm Res
Cheng YH, Thomas S, Tsang YC, Almeida S, Ashraf M, Fotaki N, Heimbach T, Patel N, Shah H, Jiang X, Kim MJ, Moody R, Rostami-Hodjegan A, Singh R, Zhao L, Babiskin A, Wu F.   +16 more
europepmc   +1 more source

Correlation Between Dissolution Profiles of Salt-Form Drugs in Biorelevant Bicarbonate Buffer and Oral Drug Absorption: Importance of Dose/ Fluid Volume Ratio. [PDF]

Pharm Res
Tarumi Y, Higashiguchi Y, Sugano K.
europepmc   +1 more source

Pre-Formulation Studies of Lipid-Based Formulation Approach for a Poorly Water-Soluble Biopharmaceutics Classification System Class II Model Drug: Bosentan. [PDF]

Turk J Pharm Sci
Yılmaz Usta D, Teksin ZŞ.
europepmc   +1 more source

Toward a Mechanistic Framework for Intestinal Drug Permeability: Integrating <i>In Silico</i> Modeling with Biorelevant Assays. [PDF]

ACS Omega
Ferreira FJN, Machado TM, Guilhon-Simplicio F.   +2 more
europepmc   +1 more source

Biorelevant in-vitro performance testing of orally administered dosage forms.

Journal of Pharmacy and Pharmacology, 2012
Objectives This review focuses on the evolution and current status of biorelevant media and hydrodynamics, and discusses the usefulness of biorelevant performance testing in the evaluation of specific dosage form related lumenal processes.
Christos Reppas, Maria Vertzoni
exaly   +1 more source

Validation of Dissolution Testing with Biorelevant Media: An OrBiTo Study

Molecular Pharmaceutics, 2017
Dissolution testing with biorelevant media has become widespread in the pharmaceutical industry as a means of better understanding how drugs and formulations behave in the gastrointestinal tract.
Lukas Klumpp, Michael Hofmann, Philippe Berben   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Theoretical modeling and prediction of biorelevant solubility of poorly soluble pharmaceuticals

Chemical Engineering Journal, 2022
Yuanhui Ji, Gabriele Sadowski, Raphaël Paus   +2 more
exaly