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Alternative Methods for Dissolution Profile Comparison in the Dissolution Test
Introduction. The article discusses the problem of assessing the similarity of the dissolution profiles of two batches of the nebivolol. The use of a generally accepted similarity factor for assessing equivalence is unacceptable in some cases, for ...
D. P. Romodanovsky, D. V. Goryachev
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Dissolution Test for Mianserin Hydrochloride in Tablets
A dissolution test for mianserin hydrochloride in coated tablets containing 30 mg was developed and validated using a fast ultraviolet spectrophotometric method.
Letícia Lenz Sfair +3 more
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Dissolution test for glibenclamide tablets
The aim of this work is to develop and validate a dissolution test for glibenclamide tablets. Optimal conditions to carry out the dissolution test are 500 mL of phosphate buffer at pH 8.0, paddles at 75 rpm stirring speed, time test set to 60 min and ...
Elisabeth Aparecida dos Santos Gianotto +4 more
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Developing and evaluation of orodispersible tablets containing caffeine [PDF]
Starting from the premise that a reduced number of active pharmaceutical ingredients (APIs) are used to treat hypotension, the aim of this study consisted of developing new formulations of caffeine-orodispersible tablets (CAFODTs).
Robert-Alexandru Vlad +7 more
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Edible Gels with Cranberry Extract: Evaluation of Anthocyanin Release Kinetics
The bioactive compounds found in cranberry fruit are natural antioxidants, and their consumption reduces the risk of diabetes, cardiovascular disease, cancers, and urinary tract infections.
Rima Šedbarė +2 more
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Validation of a UV spectrophotometric method to quantify losartan potassium in tablets from the dissolution test at pH 1.2, 4.5 and 6.8 [PDF]
Context: The validation of a method is synonymous with the quality of the obtained results. The dissolution test is an analytical technique to evaluate the quality and stability of drugs during their development.
Antonella S. Araujo-Fernandez +5 more
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The Development and the Validation of a Novel Dissolution Method of Favipiravir Film-Coated Tablets
The aim of this study was to develop and validate a dissolution test for favipiravir release in a tablet dosage form using ultra-high performance liquid chromatography (UHPLC). The dissolution method was developed by testing the solubility of favipiravir
Özge Göktuğ +3 more
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Automation of Dissolution Tests [PDF]
Dissolution testing of drug formulations was introduced in the 1960s and accepted by health regulatory authorities in the 1970s. Since then, the importance of dissolution has grown rapidly as have the number of tests and demands in quality‐control laboratories.
openaire +2 more sources
A simple liquid chromatographic method was optimized for the quantitative determination of terbinafine in pharmaceutical hydroalcoholic solutions and tablets, and was also employed for a tablet dissolution test.
Monika P. Tagliari +5 more
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Study of weight variation and dissolution of Edoxaban split tablets in pharmacy practice [PDF]
Edoxaban is available in 60 mg, 30 mg, and 15 mg unscored film-coated tablets. Tablet splitting may be an option to reduce medication costs and reduce the country’s budget.
Mantiwee Nimworapan +4 more
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