Results 11 to 20 of about 136,291 (302)
DISSOLUTION TEST IN QUALITY ASSESSMENT OF TABLETS CONTAINING 11-DEOXYMISOPROSTOL
Кубанский научный медицинский вестник, 2018 Aim. Development of the dissolution test method of 11-deoxymisoprostol tablets.Materials and methods. The research was carried out on a "paddle apparatus".
A. A. FEDOTOVA +4 more
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MODERN APPROACHES OF DISSOLUTION PROFILE TEST (REVIEW)
Разработка и регистрация лекарственных средств, 2019 Modern approaches of dissolution profile test were reviewed in terms of documents, research design, principles of choice of test conditions, selection and validation of assay methods, results evaluation and technique of the carrying out of experiment ...
D. Yu. Grebenkin +2 more
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, 2021 This dissertation explores the concept of Real Time Release applied to the dissolution of tablets. The goal is to propose an alternative appropriate quality control strategy for medicine, whose pharmaceutical formulation is a film-coated tablet containing active ibuprofen, through the analysis of the ICH Q6A guideline and other regulatory concepts. The
Freire, Tânia Sofia Rodrigues
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EVALUATION OF LINAGLIPTIN DISSOLUTION FROM TABLETS USING HPLC AND UV METHODS
Drug Analytical Research, 2019 Linagliptin (LGT) is used to reduce glucose blood levels in patients with type 2 Diabetes mellitus. The proposed conditions for a biowaiver guide can be applied due to high solubility of linagliptin in aqueous media.
Rita Elena de Abreu Engel +5 more
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Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification [PDF]
, 2017 Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance is highly or poorly soluble.
Raimar Löbenberg +13 more
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Development and validation of a dissolution test for telithromycin in coated tablets
Química Nova, 2009 A dissolution test for telithromycin tablets was validated and developed. In order to choose the most discriminatory one, the conditions to carry out are 900 mL of sodium phosphate buffer at pH 7.5, paddles at 50 rpm stirring speed, time test set to 60 ...
Lauren C. Vaucher +3 more
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Investigation of Dissolution Performance of Hard Gelatin Capsule Products Using Various Sinkers
, 2022 S.21-32Dissolution testing is a commonly used tool for the quality control of various dosage forms. For this purpose, consistent test conditions are necessary to obtain reproducible test results. Typical issues that can affect the dissolution performance
Mansuroglu, Y., Dressman, J.
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Dissolution Method Troubleshooting: An Industry Perspective
, 2022 Quality control dissolution testing represents a key product performance test for solid oral dosage forms and is the most likely QC test to result in laboratory investigations because of the relatively complex relationship between the dissolution ...
Scheubel, Emmanuel +12 more
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Química Nova, 2010 A dissolution test for in vitro evaluation of tablet dosage forms containing 10 mg of rupatadine was developed and validated by RP-LC. A discriminatory dissolution method was established using apparatus paddle at a stirring rate of 50 rpm with 900 mL of ...
Sérgio Luiz Dalmora +4 more
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Biorelevant dissolution of candesartan cilexetil
ADMET and DMPK, 2017 The choice of an appropriate medium for dissolution tests is an essential step during a dosage form development. The adequate design of dissolution testing enables forecasting in vivo behavior of drug formulation.
Lucie Gruberová, Bohumil Kratochvil
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