Results 21 to 30 of about 136,291 (302)

In vitro dissolution profile study of mucolytic drug ambroxol hydrochloride from solid oral dosage form by UHPLC-MS/MS [PDF]

Hemijska Industrija, 2017
In this paper a simplified dissolution test was performed for the release of ambroxol from tablets according to the European Pharmacopoeia. In vitro, three different dissolution media; 0.1 M HCl pH 1.2, acetate buffer (ABS) pH 4.5 and phosphate ...
Vujović Maja M., Jokanović Milan, Nikolić Goran M.   +2 more
doaj   +1 more source

Investigation of variability of primary materials on the intrinsic dissolution behavior of carbamazepine [PDF]

, 2008
Carbamazepine (CBZ) is a poorly water soluble drug, classified as class II according to the Biopharmaceutics Classification System and exhibits at least four polymorphic forms and a dihydrate.
Sehic, Selma
core   +1 more source

Dissolution Profile of Calcium Supplements in Brazil: A Critical Analysis and Formulation Proposal

, 2023
Low calcium intake is common worldwide and may lead to osteoporosis. Therefore, calcium supplementation is a vital resource to prevent fractures in patients with osteoporosis.
Rosana Pereira da Silva, Humberto Gomes Ferraz, Alexandre Gomes Rodrigues, Ferraz, Humberto Gomes, Issa, Michele George, Silva, Rosana Pereira da, Bezzon, Vinícius Danilo Nonato, Michele George Issa, Vinícius Danilo Nonato Bezzon, Rodrigues, Alexandre Gomes   +9 more
core   +1 more source

In Vitro Dissolution Studies of Immediate Release and Extended Release Formulation using Flow-through Cell Apparatus 4. Dissolution technologies [PDF]

, 2014
The aims of this study were to evaluate the dissolution performance of solid dosage forms using the open and closed modes of the FTC Apparatus 4 under different flow rates and provide examples to demonstrate the advantages of the FTC method, in ...
Qiu, S., Wang, Ke, Li, M.
core   +1 more source

3D Printed Microfluidic Devices for Drug Release Assays

Pharmaceutics, 2020
Microfluidics research for various applications, including drug delivery, cell-based assays and biomedical research has grown exponentially. Despite this technology’s enormous potential, drawbacks include the need for multistep fabrication, typically ...
Benzion Amoyav, Yoel Goldstein, Eliana Steinberg, Ofra Benny   +3 more
doaj   +1 more source

A New Method for Studying the Kinetics of the Release of Poorly Soluble API from Solid Oral Dosage Forms on the Example of Quertin®

Журнал органічної та фармацевтичної хімії, 2023
In this paper, it is proposed to consider a new method developed for studying the kinetics of release of substances that are poorly soluble in aqueous media on the example of quercetin. The study object was the drug containing plant bioactive components –
Nataliia V. Khanina, Victoriya A. Georgiyants, Vadim A. Khanin, Igor A. Zupanetz   +3 more
doaj   +1 more source

Evaluation of measurement uncertainty of the results from dissolution test of letrozole tablets using combined approaches [PDF]

Makedonsko Farmacevtski Bilten
This paper presents two simple combined approaches for estimating measurement uncertainty of dissolution tests of tablets containing 2.5 mg letrozole.
Sonja Mandovski, Hrisanta Godzo, Jelena Acevska, Natalija Nakov, Jasmina Tonic-Ribarska, Katerina Brezovska   +5 more
doaj   +1 more source

Development and assessment of a USP Apparatus 3 dissolution test method for sustained-release Nevirapine matrix tablets

, 2016
Dissolution testing is a quality control tool used to assess batch-to-batch performance of dosage forms, thereby providing continued assurance of product quality.
Mwila, Chiluba, Khamanga, Sandile M M, Walker, Roderick B   +2 more
core   +1 more source

Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets

, 2015
The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three different buffer solutions (pH 1.2, 4.
Ozturk, Naile, Kaynak, Mustafa Sinan, Sahin, Selma   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source